1. Volume 92, Issue 5, Pages 593-596 (March 1998)
Type 2 Diabetes: When Insulin Secretion Fails to Compensate for Insulin Resistance 
Barbara B Kahn 
Cell 
Volume 92, Issue 5, Pages (March 1998)
DOI: /S (00)

2. Figure 1 Insulin Signaling Pathways
IRSs, insulin responsive substrates; PDKs, phosphoinositide-dependent protein kinases; GSK3, glycogen synthase kinase 3; Akt/PKB, protein kinase B; p110, catalytic subunit; p85, regulatory subunit of phosphoinositide 3-kinase. Dotted lines indicate effects that are still under investigation.
Cell  , DOI: ( /S (00) )