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Georg Loss, PhD, Martin Depner, PhD, Laurien H. Ulfman, PhD, R. J

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Presentation on theme: "Georg Loss, PhD, Martin Depner, PhD, Laurien H. Ulfman, PhD, R. J"— Presentation transcript:

1 Consumption of unprocessed cow's milk protects infants from common respiratory infections 
Georg Loss, PhD, Martin Depner, PhD, Laurien H. Ulfman, PhD, R.J. Joost van Neerven, PhD, Alexander J. Hose, MPH, Jon Genuneit, MD, Anne M. Karvonen, PhD, Anne Hyvärinen, PhD, Vincent Kaulek, PhD, Caroline Roduit, MD, Juliane Weber, MD, Roger Lauener, MD, Petra Ina Pfefferle, PhD, DrPH, Juha Pekkanen, MD, PhD, Outi Vaarala, MD, PhD, Jean-Charles Dalphin, MD, PhD, Josef Riedler, MD, Charlotte Braun-Fahrländer, MD, Erika von Mutius, MD, Markus J. Ege, MD  Journal of Allergy and Clinical Immunology  Volume 135, Issue 1, Pages e2 (January 2015) DOI: /j.jaci Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2 Fig 1 Point prevalences of infections during the first year of life. Quartiles are marked by Q1 through Q4. Journal of Allergy and Clinical Immunology  , e2DOI: ( /j.jaci ) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3 Fig 2 Frequency of breast-feeding and infant formula during the first year of life. Quartiles are marked by Q1 through Q4. Journal of Allergy and Clinical Immunology  , e2DOI: ( /j.jaci ) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

4 Fig 3 Frequency of consumption of raw and processed cow's milk during the first year of life. Quartiles are marked by Q1 through Q4. Journal of Allergy and Clinical Immunology  , e2DOI: ( /j.jaci ) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

5 Fig 4 A-D, Adjusted associations of milk consumption and infections. Odds ratios (black circles) and 95% CI (bars) are given for associations of milk consumption with infection outcomes between week 8 and 53 weeks of life. General estimation equations adjusted for center, stable visits, breast-feeding, sex, siblings, maternal education, season of sampling, parental history of allergies, solid food score, birth mode, birth weight, contact with dogs, contact with cats, exposure to smoking, and age (squared) plus interaction terms of age with center. Rhinitis adjusted for concomitant occurrence of wheeze, otitis adjusted for concomitant occurrence of wheeze and rhinitis. Journal of Allergy and Clinical Immunology  , e2DOI: ( /j.jaci ) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

6 Fig 5 Mutually adjusted effect of milk consumption during week 8 to 53 on hsCRP levels at age 1. Geometric means ratios (black circles) and 95% CI (bars) adjusted for center, sex, older siblings, and contact with stable during first year of life. Journal of Allergy and Clinical Immunology  , e2DOI: ( /j.jaci ) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

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