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A Survival Benefit for Reduced Intensity Allogeneic Transplants from Young Unrelated Donors Compared to Older Sibling Donors Depends on the Graft CD8.

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Presentation on theme: "A Survival Benefit for Reduced Intensity Allogeneic Transplants from Young Unrelated Donors Compared to Older Sibling Donors Depends on the Graft CD8."— Presentation transcript:

1 A Survival Benefit for Reduced Intensity Allogeneic Transplants from Young Unrelated Donors Compared to Older Sibling Donors Depends on the Graft CD8 T-Cell Content  Ran Reshef, MD, Austin P. Huffman, BA, Amy Gao, MS, Mary Sell, BS MT, Marlise R. Luskin, MD, Selina Luger, MD, Alison Loren, MD, MS, Elizabeth O. Hexner, MD, Sunita D. Nasta, MD, Noelle V. Frey, MD, Saar Gill, MBBS, PhD, James Mangan, MD PhD, Lee P. Richman, BA, Taku Kambayashi, MD PhD, Edward A. Stadtmauer, MD, Robert H. Vonderheide, MD DPhil, Rosemarie Mick, MS, David L. Porter, MD  Biology of Blood and Marrow Transplantation  Volume 21, Issue 2, Pages S42-S43 (February 2015) DOI: /j.bbmt Copyright © Terms and Conditions

2 Fig. 1 CD8 cell dose and overall survival.
Biology of Blood and Marrow Transplantation  , S42-S43DOI: ( /j.bbmt ) Copyright © Terms and Conditions

3 Fig. 2 Donor age and CD8 cell dose.
Biology of Blood and Marrow Transplantation  , S42-S43DOI: ( /j.bbmt ) Copyright © Terms and Conditions

4 Fig. 3 Survival of recipients (age>60) is better with young unrelated donors and a CD8hi graft. Biology of Blood and Marrow Transplantation  , S42-S43DOI: ( /j.bbmt ) Copyright © Terms and Conditions


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