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Leptomeningeal Metastases in Patients with NSCLC with EGFR Mutations

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Presentation on theme: "Leptomeningeal Metastases in Patients with NSCLC with EGFR Mutations"— Presentation transcript:

1 Leptomeningeal Metastases in Patients with NSCLC with EGFR Mutations
Yang-Si Li, MD, Ben-Yuan Jiang, PhD, Jin-Ji Yang, PhD, Hai-Yan Tu, MS, Qing Zhou, PhD, Wei-Bang Guo, MS, Hong-Hong Yan, MS, Yi-Long Wu, MD  Journal of Thoracic Oncology  Volume 11, Issue 11, Pages (November 2016) DOI: /j.jtho Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

2 Figure 1 Study flowchart. LM, leptomeningeal metastases; WT, wild type; CSF, cerebrospinal fluid; MRI, magnetic resonance imaging. Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

3 Figure 2 Overall survival after the diagnosis of leptomeningeal metastases (LM) (n = 160). CI, confidence interval; OS, overall survival. Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

4 Figure 3 Survival curves for the 109 patients harboring common EGFR mutations. (A) Efficacy of EGFR tyrosine kinase inhibitors (TKIs) after leptomeningeal metastases (LM); (B) Efficacy of the combination of EGFR TKIs and whole brain radiotherapy (WBRT) for LM. OS, overall survival; CI, confidence interval. Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

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