1. Exo‐metabolomics profiling of major metabolites elucidated the metabolic capabilities of monospecies
Exo‐metabolomics profiling of major metabolites elucidated the metabolic capabilities of monospecies Bipartite network of species (left) and metabolites (right) for metabolites that decreased by at least twofold compared to the abundance of each metabolite at the beginning of the experiment. Colors represent modules containing many overlapping interactions in the network. Network partitioning into modules was performed using BiMat (Flores et al, 2015). Metabolites in bold were depleted and secreted by distinct organisms.Bipartite network of species (left) and metabolites (right) for metabolites that increased in abundance by at least twofold compared to the beginning of the experiment. Metabolites highlighted in bold were depleted or secreted by different species. Colors represent modules containing many overlapping interactions in the network. Network partitioning into modules was performed using BiMat (Flores et al, 2015).Scatter plot of the number of consumed metabolites that decreased by at least twofold compared to the beginning of the experiment vs. the OD600 value of the monospecies culture at the corresponding time point. Error bars represent 1 s.d. from the mean of three biological replicates.Predicted resource utilization interaction network. Each edge represents at least two co‐consumed metabolites that decreased by at least twofold, and the edge width is proportional to the number of co‐consumed metabolites. Node size is proportional to the total number of consumed metabolites for each species.Predicted metabolite interchange network representing metabolites that were secreted or utilized by distinct organisms based on a twofold threshold. Arrows point from the source species to the consumer organism. Node size and line width are proportional to the total number of secreted metabolites and number of predicted metabolite interactions, respectively. Species at the top and bottom of the network are primarily producers or consumers, respectively.
Ophelia S Venturelli et al. Mol Syst Biol 2018;14:e8157
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