1. RESPIRATION & OXIDATION

2. GLYCOLYSIS Step 1: Phosphorylation:
Glucose + 2ATP  Fructose 1,6-diphosphate + 2ADP
Step 2: Splitting 6C sugar to 2 x 3C sugars:
Fructose 1,6-diphosphate  2 Glyceraldehyde Phosphate
Step 3: Energy release: 2 ATP molecules recuperated plus… 2 ATP directly synthesised plus…
2 Glyceraldehyde Phosphate  2 Pyruvate
4ADP
4ATP
© 2016 Paul Billiet ODWS

3. KREBS CYCLE
Enzymes located in the inner matrix of mitochondria (in eukaryotes)
Note: Number of mitochondria per cell = activity of the cell On average 1000 per cell (between 20 and ).

4. Inner matrix
Cristae
Inter membrane space
outer membrane
Mitochondrial envelope
inner membrane
Viewed using electron tomography

5. Step 1: Synthesising ACETYL COENZYME A
Also produced from fatty acids and amino acids
Pyruvate  Acetyl CoA + CO2 (3C) (2C) (1C) CYTOPLASM  MITOCHONDRIA
3ADP 3ATP

6. Step 2: Oxidising Acetyl CoA
back to the cytoplasm
Acetyl CoA + Oxaloacetate Citrate + CoA (2C) (4C) (6C)
KREBS CYCLE
Breathed out or used by chloroplasts
2CO2
4H2O
4 x 1/2O2
12ATP 12ADP

7. The Krebs Cycle, discovered by using inhibitors and isolating enzymes from tissues rich in mitochondria
Total ATP from 1 molecule of glucose in AEROBIC CONDITIONS
Glycolysis - 2 (phosphorylation) + 8 Krebs Cycle (2x15) TOTAL ATP

8. Complete Krebs

9. Complete Krebs