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Epigenetics, infertility, and cancer: future directions

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Presentation on theme: "Epigenetics, infertility, and cancer: future directions"— Presentation transcript:

1 Epigenetics, infertility, and cancer: future directions
Emma James, B.S., Timothy G. Jenkins, Ph.D.  Fertility and Sterility  Volume 109, Issue 1, Pages (January 2018) DOI: /j.fertnstert Copyright © Terms and Conditions

2 Figure 1 Some of the most common epigenetic marks that are associated with gene activation or repression. DNA methylation at promoters at cytosine-phosphate-guanine (CpG) dinucleotides can regulate the activation or silencing of gene transcription. Similarly, histone modifications including ubiquitination (ub), monomethylation (me), dimethylation (me2), trimethylation (me3), and acetylation (ac) at various histones (H3, H2A, H4, H2B, etc.) can drive gene regulation. These histone modifications typically occur at histone tails on lysine residues (K4, K9, K27, etc.). Fertility and Sterility  , 27-32DOI: ( /j.fertnstert ) Copyright © Terms and Conditions


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