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Figure 1 Model of mechanosensation through primary cilia

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Presentation on theme: "Figure 1 Model of mechanosensation through primary cilia"— Presentation transcript:

1 Figure 1 Model of mechanosensation through primary cilia
Figure 1 | Model of mechanosensation through primary cilia. a | Bending of primary cilia by fluid flow results in a cytosolic Ca2+ signal. Delling et al. now report that this Ca2+ signal is not initiated in the primary cilium (dotted line)7. b | The activation mechanism of the polycystin complex (PC1, TRPP2) and its Ca2+-dependent downstream effectors remain elusive. ER, endoplasmic reticulum. Hofherr , A. & Köttgen, M. (2016) Cilia and mechanosensation revisited Nat. Rev. Nephrol. doi: /nrneph

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