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Figure 4 Interactions between adipose, the microbiome and kidney

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Presentation on theme: "Figure 4 Interactions between adipose, the microbiome and kidney"— Presentation transcript:

1 Figure 4 Interactions between adipose, the microbiome and kidney
Figure 4 | Interactions between adipose, the microbiome and kidney. Alterations in microbiota in the presence of increased adiposity and renal dysfunction, arising from the effects of adipose-derived factors and uraemic toxins, respectively, could disrupt intestinal homeostasis, leading to leakage of inflammatory factors from the gut and amplification of inflammatory responses. Conversely inflammation within the damaged kidney could directly induce the migration and activation of immune cells into adipose tissue, further inducing inflammation and the release of adipose-derived factors. Câmara, N. O. S. et al. (2017) Kidney disease and obesity: epidemiology, mechanisms and treatment Nat. Rev. Nephrol. doi: /nrneph

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