Presentation is loading. Please wait.

Presentation is loading. Please wait.

Figure 5 Dendritic cells in liver inflammation

Published byDwight Sullivan Modified over 5 years ago

Similar presentations

Presentation on theme: "Figure 5 Dendritic cells in liver inflammation"— Presentation transcript:

1 Figure 5 Dendritic cells in liver inflammation
Figure 5 | Dendritic cells in liver inflammation. Dendritic cells are mainly triggered via TLR ligands and generally show immunoregulatory properties in the liver, secreting IL-10 and suppressing T cells via PD-L1, but also can induce stress responses via HMGB1 and TNF secretion for example, in NAFLD. In viral hepatitis and also metabolic liver disease, they can become immunogenic, activating CD4+ and CD8+ T cells and secrete pro-inflammatory cytokines. DC, dendritic cell; FFA, free fatty acid; HMGB1, high mobility group box protein 1; LPS, lipopolysaccharide; MHC, major histocompatibility complex; MMP, matrix metalloproteinase; PD-L1, programmed death ligand 1; TLR, Toll-like receptor. Heymann, F. & Tacke, F. (2016) Immunology in the liver — from homeostasis to disease Nat. Rev. Gastroenterol. Hepatol. doi: /nrgastro

Download ppt "Figure 5 Dendritic cells in liver inflammation"

Similar presentations

Biochemical Markers in the inflammatory response Dr Claire Bethune Consultant Immunologist Derriford Hospital.

Biochemical Markers in the inflammatory response Dr Claire Bethune Consultant Immunologist Derriford Hospital.
Activation of T Lymphocytes

Activation of T Lymphocytes
Targeting Immune Checkpoints in Esophageal Cancer: A High Mutational Load Tumor  Rajeev Dhupar, MD, Lauren Van Der Kraak, PhD, Arjun Pennathur, MD, Matthew.

Targeting Immune Checkpoints in Esophageal Cancer: A High Mutational Load Tumor  Rajeev Dhupar, MD, Lauren Van Der Kraak, PhD, Arjun Pennathur, MD, Matthew.
Intermyocellular fat depot

Intermyocellular fat depot
Figure 2 Inflammatory pathways affecting hepatic insulin resistance

Figure 2 Inflammatory pathways affecting hepatic insulin resistance
Figure 1 CTLA-4 and PD-1–PD-L1 immune checkpoints

Figure 1 CTLA-4 and PD-1–PD-L1 immune checkpoints
CD46: role in multiple sclerosis

CD46: role in multiple sclerosis
Dendritic Cell Immunotherapy for the Treatment of Neoplastic Disease

Dendritic Cell Immunotherapy for the Treatment of Neoplastic Disease
Figure 2 Cell-mediated disease mechanisms of lupus nephritis

Figure 2 Cell-mediated disease mechanisms of lupus nephritis
Figure 2 Exosome composition

Figure 2 Exosome composition
Figure 5 Involvement of B cells in SLE

Figure 5 Involvement of B cells in SLE
Figure 3 Neutrophils in liver inflammation

Figure 3 Neutrophils in liver inflammation
Figure 1 Radiation-induced effects on tumour cells

Figure 1 Radiation-induced effects on tumour cells
Figure 1 Differential immune responses in the gut (oral tolerance)

Figure 1 Differential immune responses in the gut (oral tolerance)
Figure 2 Immune-escape mechanisms of CTCs in the peripheral blood

Figure 2 Immune-escape mechanisms of CTCs in the peripheral blood
Figure 1 Contribution of the gut microbiota

Figure 1 Contribution of the gut microbiota
The inflammasome in liver disease

The inflammasome in liver disease
Nat. Rev. Gastroenterol. Hepatol. doi: /nrgastro

Nat. Rev. Gastroenterol. Hepatol. doi: /nrgastro
Nat. Rev. Gastroenterol. Hepatol. doi: /nrgastro

Nat. Rev. Gastroenterol. Hepatol. doi: /nrgastro
Volume 17, Issue 6, Pages (June 2013)

Volume 17, Issue 6, Pages (June 2013)

Similar presentations

Ads by Google