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Microarray analysis each spot represents one gene Yellow: no change in

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Presentation on theme: "Microarray analysis each spot represents one gene Yellow: no change in"— Presentation transcript:

1 Microarray analysis each spot represents one gene Yellow: no change in
gene expression Green: the gene is turned off in the tumor Red: the gene is turned on in the tumor

2 Analyzing Human Breast Cancer Types By Microarray Analysis

3 Identifying genes whose expression changes at specific stages of the cell cycle

4 Implications for sleep disorders
day night day night day night Circadian Rhythms and Sleep Genes whose expression changes during the day in fruit flies (and people) Implications for sleep disorders

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6 Arp3 Arp2 Arc40 Arc35 Arc19 Arc18 Arc15 Example from Bruce Goode,

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8 Fig. 1. Representation of chromosome V incorporating genetic footprinting data. Each box is colored to summarize the results obtained to date from genetic footprinting. Mutant phenotypes: Q1, all selections, <75% population growth rate; Q2, all selections, 75 to 85% population growth rate; Q3, all selections, 85 to <100% population growth rate. Genes in which mutations gave distinctive phenotypes under specific selections are colored according to the selection(s) affected, as follows: M: (dark green),: minimal medium;. L (teal),: lactate medium;. H (orange),: high temperature;. C (brown),: caffeine;. S (yellow),: high salt;. X (light green),: mating;. WT (dark blue),: wild-type for all selections;. NR (grey)

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16 bim1 x rad54

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