1. Macromolecules: Proteins

2. Bell work
Why does your body need proteins to function?

3. Objectives Explain why a protein is a polymer
List the different functions of proteins
Describe the four levels of protein structure

4. Key Terminology Amino acid Enzymes Peptide Bond Primary Structure
Secondary Structure
Tertiary Structure
Quaternary Structure

5. Proteins
Polymers of amino acids
Have diverse shapes & functions

6. Diverse Functions of Proteins Include:
Anchor
provide support & protection
Transporter
move ions and small molecules across membranes

7. Diverse Functions of Proteins Include:
Enzyme
act as catalysts to speed up chemical reactions
Receptor
bind chemical signals, like hormones

8. Think-Pair-Share
Describe an example of a protein and its function. Be ready to share
3. Think-pair-share
teacher presents a question
teacher gives wait time for student to form answer
teacher instructs students to share their answer with a partner
teacher calls on non-volunteers to share with the class 3 8

9. Structure of an Amino Acid
Amino acids have basic structure as shown
R group varies between amino acids
20 different type of R groups
20 different amino acids

10. Amino acids linked together by a Peptide Bond
is a covalent bond

11. Four levels of Protein Structure
Primary structure
order of amino acids
each protein has a unique sequence of amino acids
Cannot function as a long chain of amino acids
must continue to fold into a unique shape
Secondary structure
amino acids within the chain become twisted or folded

12. Four Levels of Protein Structure
Tertiary structure
chain folds upon itself to 3-D structure
Quaternary structure
May have more than one protein chain
Multiple chains link together

13. Summary of the 4 levels

14. Example: Hemoglobin Function: transport oxygen in blood
Shape: “globular”
with binding sites for 4 oxygen molecules

15. Example: Hemoglobin Has Quaternary Structure
Made of 2 alpha subunits and 2 beta subunits

16. Think-Pair-Share Be ready to share
Proteins have diverse functions. What is it about proteins that allow them to be so diverse?
Be ready to share
3. Think-pair-share
teacher presents a question
teacher gives wait time for student to form answer
teacher instructs students to share their answer with a partner
teacher calls on non-volunteers to share with the class 16

17. Minute Paper
You have one minute on your note-taker to write down key points of today’s lesson.
Be ready to share.
29. Minute paper or Quick Write
teacher provides a prompt from the lesson
students have one minute to write down a summary of the key points
students compare with a partner
teacher uses a strategy to check all 17