1. Bipolar I Depression Today: The Evolving Understanding of Bipolar Depression Neurobiology and the Relation to Diagnosis

2. Program Goals

5. MDD With Subthreshold Hypomania Tends to Become BPD Over Time

8. Features Nominally Associated With Time to Recurrence in Bipolar Disorder (All P < .05)

9. Screening and Diagnostic Tools

10. Biological Vulnerability

13. Neurotransmitter Changes and Symptoms of Mood Disorders

15. Progression and Acceleration of the Disease Process

18. Conclusion

19. Abbreviations

20. References

21. References (cont)

22. References (cont)

23. References (cont)

24. References (cont)

25. References (cont)