1. gt 3
gt 1
gt 2
gt 4
swHEV sw-NL Netherlands (EU526647)
swHEV sw-NL Netherlands (EU526646)
wbHEV WBGER27 Germany (FJ705359)
huHEV Germany (KF373757)
huHEV TR32 France (GU196324)
wbHEV 118E Germany (EU035812)
wbHEV 119E Germany (EU035813)
wbHEV 13464E Germany (EU035815)
wbHEV 108S Germany (EU035811)
wb HEV 149E Germany (EU035814)
huHEV US1 USA (AF060668)
huHEV JJT-Kan Japan (AB091394)
swHEV RSA-1 South Africa (AY621664)
swHEV MN06-A1288 Mongolia (AB290312)
swHEV Osh 205 Kirgizia (AF455784)
wbHEV SA21 Germany (FJ998015)
huHEV RKI Germany (FJ956757)
huHEV SAR-55 Pakistan (M80581)
huHEV Mexican Mexico (M74506)
huHEV T1 China (AJ272108) 61 52 84 88 72 78 77
0.1
Supplementary Figure 1: Phylogenetic relationship of the HEV sequence derived from serum sample (indicated in boldface) together with human, pig, and wild boar derived HEV strains. The sequences were selected based on a sequence similarity search using the BLASTn search facility, and additional reference strains were included. The origin of the virus sequences (sw, swine; hu, human; wb, wild boar), strain designation, country of detection, and the GenBank accession numbers are indicated. Grouping of the sequences into genotypes is shown on the right. The tree was constructed with a 147-nucleotide fragment of the HEV ORF2. The phylogenetic analysis was conducted with MEGA5 using the ML method [58] and bootstrap values of ≥50% are shown on the branches.