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The DNA Connection
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Chromosomes are made of DNA
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The DNA Code
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Each chromosome contains thousands of genes.
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The sequence of bases in a gene forms a code
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Every 3 Letters is called a CODON
Code = protein
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DNA carries the codes
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DNA Deoxyribonucleic Acid (DNA) Double Stranded
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DNA Bases Purines: 1. Adenine (A) 2. Guanine (G)
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Pyridimines 1. Cytosine (C) 2. Thymine (T)
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DNA Base Pairing A=T G C
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RNA Base Pairing A=U *Uracil There is NO “T” in RNA G C
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Transcription
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The process by which RNA is made from DNA
Occurs in the Nucleus
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Since DNA is too big to fit through the nuclear pores, messenger RNA is used to “read” DNA
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RNA Single Stranded Same bases as DNA EXCEPT instead of T RNA contains U
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After transcription mRNA leaves the nucleus and attaches onto a ribosome
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Translation
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The message is translated into an amino acid sequence
Occurs on ribosomes
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Every 3 Letters is called a CODON
Code = protein
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Requires tRNA to translate the code
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tRNA can only read 3 mRNA codes at one time (codon)
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The Genetic Code The Codon codes for which amino acid is to be made
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Amino Acids – the building blocks of proteins
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mRNA codon UAC Translated Code Tyr
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DNA Sequence: A T G C A A T G C U A C G U U A C G
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RNA Sequence: UAC GUU ACG Amino Acids Produced: Tyr – Val – Thr
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DNA Mutations
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Substitution
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Deletion
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Addition
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