1. (CMR vs. guidelines, p < 0.001)
CE-MARC 2
Trial design: Patients with suspected CHD were randomized to CMR-guided care (n = 481) versus MPS-guided care (n = 481) versus NICE guideline-directed care (n = 240).
Results
(CMR vs. guidelines, p < 0.001)
CMR vs. MPS, p = 0.32)
Unnecessary invasive angiography: 7.5% of the CMR group vs. 7.1% of the MPS group vs. 28.8% of the NICE guideline-directed care group (CMR vs. NICE, p < 0.001; CMR vs. MPS, p = 0.32)
MACE at 12 months: 2.5% of the CMR group vs. 2.5% of the MPS group vs. 1.7% of the NICE guideline-directed care group (CMR vs. NICE, p = NS; CMR vs. MPS, p = NS) %
28.8
7.5
7.1
Conclusions
Among patients with suspected CHD, CMR-guided care resulted in a lower frequency of unnecessary invasive angiography versus NICE guideline-directed care
CMR group
MPS group
Guideline-directed care group
Greenwood JP, et al. JAMA 2016;316: