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Epidermal Growth Factor Receptor-Related Tumor Markers and Clinical Outcomes with Erlotinib in Non-small Cell Lung Cancer: An Analysis of Patients from.

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Presentation on theme: "Epidermal Growth Factor Receptor-Related Tumor Markers and Clinical Outcomes with Erlotinib in Non-small Cell Lung Cancer: An Analysis of Patients from."— Presentation transcript:

1 Epidermal Growth Factor Receptor-Related Tumor Markers and Clinical Outcomes with Erlotinib in Non-small Cell Lung Cancer: An Analysis of Patients from German Centers in the TRUST Study  Claus-Peter Schneider, MD, David Heigener, MD, Kathrin Schott-von-Römer, MD, Sylvia Gütz, MD, Eckart Laack, MD, Werner Digel, MD, Wolf-Rüdiger Guschall, MD, Andreas Franke, MD, Heinrich Bodenstein, MD, Claudia Schmidtgen, PhD, Martin Reck, MD, PhD  Journal of Thoracic Oncology  Volume 3, Issue 12, Pages (December 2008) DOI: /JTO.0b013e31818ddcaa Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions

2 FIGURE 1 Progression-free (A) and overall survival (B) during treatment with erlotinib. Journal of Thoracic Oncology 2008 3, DOI: ( /JTO.0b013e31818ddcaa) Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions

3 FIGURE 2 Survival outcomes according to tumor marker status. Epidermal growth factor receptor (EGFR), fluorescence in situ hybridization (FISH) (A), EGFR mutation analysis (B) and KRAS mutation analysis (C). Journal of Thoracic Oncology 2008 3, DOI: ( /JTO.0b013e31818ddcaa) Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions

4 FIGURE 3 Progression-free survival (PFS) (A) and overall survival (OS) (B) according to phosphorylated mitogen-activated protein kinase (pMAPK) status (immunohistochemistry). Journal of Thoracic Oncology 2008 3, DOI: ( /JTO.0b013e31818ddcaa) Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions

5 FIGURE 4 Epidermal growth factor receptor (EGFR), immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) status in adenocarcinomas (A) and squamous cell carcinomas (B). Journal of Thoracic Oncology 2008 3, DOI: ( /JTO.0b013e31818ddcaa) Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions

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