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DENTIFRICES.

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Presentation on theme: "DENTIFRICES."— Presentation transcript:

1 DENTIFRICES

2 A substance used with a toothbrush for the purpose of cleaning the accessible surfaces of teeth
Types 1. Cosmetic Dentifrices: It must clean and polish the teeth 2. Therapeutic Dentifrices: Must reduce some disease process

3 Ingredients • Abrasives 20%-40% (Silicon Oxide, Aluminum Oxide, Granular polyvinyl Chloride) • Water 20%-40% • Humectants 20%-40% (Sorbitol, Mannitol, Propylene glycol, Glycerine) • Foaming agents 1%-2% (Sodium lauryl sulfate, sodium N-lauroyl sarcosinate) • Sweetening agent 2% (Sorbitol, Mannitol, Glycerine) • Binding agent 2% • Flavoring agent 2% • Therapeutic agent (Fluoride, tetra sodium phosphate) 2% • Preservative (benzoic acid) colouring agent 1%

4 Abrasive agent: Helps to polish tooth by eliminating calculus food,
particles stuck on tooth Humectant: prevents drying of toothpaste and to maintain consistency of Toothpaste. Foaming agent: Aids in removal of food debris Flavoring agent: for Pleasant feel after mouth wash Antibacterial agent (Triclosan): For reduction of Gingivitis, calculus etc Fluorides(monofluoroPO4): To make teeth more resistant to the acids produce by bacteria Binding/Thickening agent (alginate, NaCMC, Sod Magnesium Silicate): Stability & consistency Anticalculus agents (Zinc Citrate, Zinc PO4, pyro PO4): To inhibit minerlization of Plague

5 Different forms Pastes Tooth powder Gels

6 Hair Creams

7 HAIR COSMETICS 1 HAIR TONICS 2 3 HAIR REMOVERS 4 5 SHAVING PREPARATION

8 HAIR TONICS For Oily Scalps: To correct the oily condition……
For Dry scalps: to supplement oily character…..

9 Ingredients Industrial methylated spirit diluted with water : common vehicle. 10-95% alcohol act as a solvent for the removal of fatty acid – protein complex from hair. 2-5% glycerin : emollient and lubricating effect and act as a co solvent. Rubifacient drugs to stimulate hair growth. Eg: cantharides, pilocarpine, quinine, ammonia, rosemary oil… Vitamins: Vit K , biotin, pantothenic acid. Anti dandruff material: sulphur, cationic surfactants,selinium and cadmium sulphide etc. Antiseptic: Resorcinol (<1%), Beta naphthol (< 0.1%), Quinine

10 Hair conditioner alter the texture and appearance of human hair and to improve damaged hair. Used after shampoo, to render the hair shinier, easy to comb, and free from static electricity when dry. Conditioners are usually based on cationic detergents and fatty materials like lanolin or mineral oil.

11 Ingredients 1. Moisturizers.
To hold moisture in the hair. Contain high proportions of humectants. 2. Re constructors. Usually containing hydrolyzed protein. Their role is to penetrate the hair and strengthen its structure through polymer cross linking. 3. Detanglers. Which modify the hair surface by pH as acidifiers ( ), and/or by coating it with polymers, as glossers.

12 Surfactants. Hair consists of approximately 97% of a protein called keratin, negatively-charged amino acids Hair conditioners therefore usually contain cationic surfactants, which don't wash out completely, because their hydrophilic ends strongly bind to keratin. The hydrophobic ends of the surfactant molecules then act as the new hair surface. Oils (EFAs): become more soft Lubricants: fatty alcohols, panthenol, dimethicone, etc for better function in hard water.

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14 HAIR REMOVERS EPILATORIES DEPILATORIES Chemical Mechanical
For removing unwanted hairs. Several methods like waxing threading etc… Other various methods are electrolysis and diathermy.

15 Depilatories For degradation of superficial hair chemically without affecting the skin. Act by degrading the hair keratin. Contain alkaline solutions and reducing agents. Which cause swelling of hair fiber and breakdown of cystine bridges between adjacent polypeptide chains.

16 Formula Strontium sulphide Talc Methyl cellulose Glycerine Water Perfume Preservative 20g 20g 3g 15g 42g q.s q.s

17 Ingredients Sodium sulphide: (2%) at pH 12 (not used due to
1. Inorganic Sulphides : Sodium sulphide: (2%) at pH 12 (not used due to strong action on skin) Barium sulphide: highly toxic Calcium sulphide: less toxic, less effective. Strontium sulphide: better choice.(25-50%) action within 3 min. Disadv: unpleasent odour (formation of hydrogen sulphide)

18 3. Stannites : 2.Thioglycolates :
Most widely used active ingredient are substituted mercaptans Used in conjugation with alkali 2.5 – 4% of calcium thioglycolate in conjugn with CaOH at pH take 5-15 min for hair removal. Less toxic and less odour than sulphides. 3. Stannites : Sodium stannite is commonly used In presence of water it produces strong reducing and alkaline effect

19 4. Enzymes : Keratinase enzyme have depilatory action Non irritant and odourless 3-4%is used and optimum pH is 7-8 5. Other additives : Humectant : prevent quick drying Eg: Glycerin, Sorbitol Thickening Agent: Starch, Methylcellulose, Mucin. PEG used to form film. Fat used for skin protection & conditioning.

20 EPILATORIES Plucking the hair either by tweezers, threading or by waxing. Rosin and wax are the main ingredient. Local anesthetic benzocain. Camphor, Hexachlorophane is also added.

21 Ideal Characters of hair Creams
Advantages of Creams prolong contact Non-irritating when appliedtotheskin. Easily water washable. Easy to wipe away. Less greasy compared toointment. Easy to spread on the skin's surface (i.e. easy to apply). Ideal Characters of hair Creams It should liquefy at body temperature. It should penetrate the epidermis (via natural opening). Its viscosity should be low enough to permit easy spreading. non-toxic. non-irritant. non-inflammatory.

22 Evaluation pH of the cream Viscosity
Rheological behavioral of the cream Determination of type of emulsion i. Dilution test ii. Dye solubility test Stability Globule size Phase separation Moisture absorption studies Shelf life Spreadability Study of skin morphology - evaluation of gross or microscopic changes in the physical appearance of the skin, skin smoothness, elasticity

23 Manicure preparations

24 Nail is composed of three layers:
The nail normally grows distally at the rate of 0.1 mm per day.

25 Nail is composed of Hard Keratin Calcium ( Very Low - Not More Than 2 Parts Per 1000 By Weight) Fatty Materials (Cholesterol) Water (12-14% ) Preparations Nail lacquer (nail varnish) Nail polish Nail hardener Nail enamel remover Nail Moisturizer Cuticle remover Nail elongator

26 NAIL LACQUER (NAIL VARNISH)
It is type of preparation from the transparent uncolored or pale pink natural colors. The ideal requirements are It should be easy & convenient to apply. Stable on storage with regards to homogeneity, separation, sedimentation, color etc. Should give the film with satisfactory characteristics. Waterproof, well-adherent, glossy, elastic. Resistant to chipping and abrasion. Non-toxic and dermatologically innocuous (harmless). Characteristics of satisfactory film Evenness, achieved by satisfactory viscosity. Uniform color distribution, achieved by finly divided pigments. Good gloss, which implies a very smooth surface. Good adhesion to nail. Flexibility to avoid brittleness and cracking. Hard, non sticky, resistant to impact & scratching. Satisfactory drying time I,e 1-2 minutes with development of bloom in humid atmospheres. Maintenance of said properties for approximately one week.

27 Ingredients of Nail Laquer
Primary film former (nitrocellulose, methacrylate polymers, vinyl polymers) Secondary film-forming resin (formaldehyde, p- toluene sulfonamide, polyamide, acrylate, alkyd, vinyl resins) Plasticizers (dibutyl phthalate, dioctyl phthalate, tricresyl phosphate, camphor) 20-50% Solvents and diluents (acetates, ketones, toluene, xylene, alcohols) Colorants (organic D&C pigments, inorganic pigments) Specialty fillers Pearlescent pigments (guanine, fish scale, titanium dioxide–coated mica flakes, or bismuth oxychloride for iridescence) Suspending agents (0.5-2%)

28 Resistance to soaps & detergents Eveness & gloss Abrasion test
Formula Nitrocellulose 10% Resin Plasticizer Alcohol Ethyl acetate 20 Butyl acetate 15 Toluene Evaluation test: Drying time Appearance Hardness Adhesion Resistance to soaps & detergents Eveness & gloss Abrasion test

29 Nail Polish Prior to 1920, nails were manicured and then rubbed with abrasive powder to achieve a shine. Color was added through the use of stains. In 1930, Charles Revson developed the first pigmented, opaque nail polish, which launched Revlon, still a major manufacturer of nail cosmetics today. Nail polish basically consists of pigments suspended in a volatile solvent to which film formers have been added.

30 Nail Hardener Nail hardeners are used to increase the strength of brittle nails caused by nail plate dehydration due to excessive contact with solvents, detergents, and water. Originally, nail hardeners were formulated as 10% or greater solutions of formaldehyde; however, FDA recalled these products following reports of onycholysis, subungual hyperkeratosis, reversible subungual hemorrhage, bluish discoloration of the nail plate, and allergic contact dermatitis in the dermatologic literature. Free formaldehyde (1-2%) is still permitted, but acetates, toluene, nitrocellulose, acrylic, and polyamide resins are now used to structurally reinforce the nail plate. Some products actually contain 1% nylon fibers and are known as fibered nail hardeners. Other additives purported to strengthen the nail include hydrolyzed proteins, modified vegetable extracts, glycerin, propylene glycol, and metal salts.

31 Nail Enamel Remover Formulation Nail polish removers are liquids designed to strip the nail polish from the nail plate. They may contain strong solvents, such as acetone, alcohol, ethyl acetate, or butyl acetate Formula Butyl stearate % Diethylene glycol monoethyl ether Acetone

32 Cuticle Remover The cuticle can be removed Mechanically
Chemically (liquids or creams that contain an alkali to destroy cuticle keratin). The active agent is usually 2-5% sodium hydroxide or potassium hydroxide with propylene glycol or glycerin added as a humectant. cuticle softeners: Milder preparations can be made with trisodium phosphate or tetrasodium pyrophosphate, but they are also less effective. These products are quaternary ammonium compounds (3-5% ), and they are sometimes combined with urea

33 Formula Trisodium phosphate 8% Glycerin Water Perfume q.s. Nail Moisturizer The healthy nail contains about 16% water, becoming soft with saturation at 30%. Nail moisturizers are usually creams or lotions that contain Occlusives, such as petrolatum, mineral oil, or lanolin. Humectants, such as glycerin, propylene glycol, and proteins Water binding capacity: Alpha-hydroxy acids, lactic acid, and urea

34 Nail Elongators Methods of creating the illusion of nail length. This technique can be accomplished through the use of preformed plastics, formed acrylics, or a combination of both methods.


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