Presentation is loading. Please wait.

Presentation is loading. Please wait.

The association of lowest hematocrit during cardiopulmonary bypass with acute renal injury after coronary artery bypass surgery  Madhav Swaminathan, MD,

Similar presentations


Presentation on theme: "The association of lowest hematocrit during cardiopulmonary bypass with acute renal injury after coronary artery bypass surgery  Madhav Swaminathan, MD,"— Presentation transcript:

1 The association of lowest hematocrit during cardiopulmonary bypass with acute renal injury after coronary artery bypass surgery  Madhav Swaminathan, MD, Barbara G Phillips-Bute, PhD, Peter J Conlon, MD, Peter K Smith, MD, Mark F Newman, MD, Mark Stafford- Smith, FRCPC  The Annals of Thoracic Surgery  Volume 76, Issue 3, Pages (September 2003) DOI: /S (03)

2 Fig 1 This figure is based on a predictive model for “typical” patients relating lowest hematocrit (Hct) during bypass to peak percentage change in creatinine (%ΔCr), where the following covariates were adjusted for: prebypass glucose = 130 mg/dL, Charlson comorbodity score = 1, preoperative hematocrit = 40%, preoperative creatinine = 1.5 mg/dL, and no intraaortic balloon pump, inotropes, transfusion, or diabetes. The regression equations are %ΔCr = for 75 kg (triangles), (lowest Hct during bypass*0.604); for 100 kg (asterisks), (lowest Hct during bypass*−0.791); for 125 kg (circles), (lowest Hct during bypass*−2.186); for 150 kg (squares), (lowest Hct during bypass*−3.581). The Annals of Thoracic Surgery  , DOI: ( /S (03) )

3 Fig 2 The relationship of lowest hematocrit (Hct) during bypass to peak percentage change in creatinine (%ΔCr) in patients (n = 776) with weight 75 kilos or more, with 95% confidence limits (dashed lines). The regression equation is %ΔCr = (lowest Hct during bypass*−1.10). The Annals of Thoracic Surgery  , DOI: ( /S (03) )

4 Fig 3 This figure is based on a predictive model for “typical” patients relating lowest hematocrit (Hct) during bypass to (CrmaxPost), where the following covariates were adjusted for: prebypass glucose = 130 mg/dL, Charlson comorbodity score = 1, preoperative hematocrit = 40%, preoperative creatinine = 1.5 mg/dL, and no intraaortic balloon pump, inotropes, transfusion, or diabetes. The regression equations are CrmaxPost = for 75 kg (triangles), (lowest Hct during bypass*0.007); for 100 kg (asterisks), (lowest Hct during bypass*−0.006); for 125 kg (circles), (lowest Hct during bypass*−0.03); for 150 kg (squares), (lowest Hct during bypass*−0.05). The Annals of Thoracic Surgery  , DOI: ( /S (03) )

5 Fig 4 The influence of blood transfusion on the relationship between lowest hematocrit (Hct) during cardiopulmonary bypass and peak postoperative fractional change in creatinine (%ΔCr). RBCs: 9 (asterisks); 6 (triangles); 3 (circles); 0 (squares). (RBCs = number of units of packed red blood cells transfused intraoperatively.) The Annals of Thoracic Surgery  , DOI: ( /S (03) )


Download ppt "The association of lowest hematocrit during cardiopulmonary bypass with acute renal injury after coronary artery bypass surgery  Madhav Swaminathan, MD,"

Similar presentations


Ads by Google