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Less Is More: Results of a Statewide Analysis of the Impact of Blood Transfusion on Coronary Artery Bypass Grafting Outcomes Todd C. Crawford, MD, J. Trent Magruder, MD, Charles Fraser, MD, Alejandro Suarez-Pierre, MD, Diane Alejo, BA, Jennifer Bobbitt, BA, Clifford E. Fonner, BA, Joseph K. Canner, MHS, Keith Horvath, MD, Kurt Wehberg, MD, Bradley Taylor, MD, Christopher Kwon, MD, Glenn J. Whitman, MD, John V. Conte, MD, Rawn Salenger, MD The Annals of Thoracic Surgery Volume 105, Issue 1, Pages (January 2018) DOI: /j.athoracsur Copyright © 2018 The Society of Thoracic Surgeons Terms and Conditions
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Fig 1 Comparison of the average number of red blood cell (RBC) units transfused per patient adjusted for The Society of Thoracic Surgeons (STS) predicted risk of mortality. Thus, the y-axis represents the average number of RBC units transfused per 1% STS predicted risk of mortality. Each of the 10 bubbles corresponds to Maryland cardiac surgery site, and the size of the bubble is relative to the number of coronary artery bypass grafting operations performed during the study period. (MCSQI = Maryland Cardiac Surgery Quality Initiative.) The Annals of Thoracic Surgery , DOI: ( /j.athoracsur ) Copyright © 2018 The Society of Thoracic Surgeons Terms and Conditions
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Fig 2 (Left) Propensity score distribution of patients who did not receive a transfusion (untreated) and those who did (treated). (Right) The coefficients for each of the variables comprising the propensity score are included. (CHF = congestive heart failure; CI = confidence interval; GFR = glomerular filtration rate; IABP = intraaortic balloon pump; LL = lower limit; LVEF = left ventricular ejection fraction; MI = myocardial infarction; UL = upper limit.) The Annals of Thoracic Surgery , DOI: ( /j.athoracsur ) Copyright © 2018 The Society of Thoracic Surgeons Terms and Conditions
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Fig 3 Kaplan-Meier 30-day survival curves comparing propensity-matched patients who did not receive a transfusion and those who did. (CI = confidence interval.) The Annals of Thoracic Surgery , DOI: ( /j.athoracsur ) Copyright © 2018 The Society of Thoracic Surgeons Terms and Conditions
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Fig 4 Kaplan-Meier curves comparing the probability of remaining hospitalized at 14 days between propensity-matched patients who did not receive a transfusion and those who did. (CI = confidence interval.) The Annals of Thoracic Surgery , DOI: ( /j.athoracsur ) Copyright © 2018 The Society of Thoracic Surgeons Terms and Conditions
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Fig 5 Kaplan-Meier curves comparing the probability of remaining intubated at 24 hours between propensity-matched patients who did not receive a transfusion and those who did. (CI = confidence interval.) The Annals of Thoracic Surgery , DOI: ( /j.athoracsur ) Copyright © 2018 The Society of Thoracic Surgeons Terms and Conditions
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Fig 6 Summary of secondary outcomes among propensity-matched patients who did not and did receive a blood transfusion. Incidences of prolonged ventilation, renal failure, and surgical site infection were not statistically different between groups. (CABG = coronary artery bypass grafting.) The Annals of Thoracic Surgery , DOI: ( /j.athoracsur ) Copyright © 2018 The Society of Thoracic Surgeons Terms and Conditions
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Supplemental Fig 1 The Annals of Thoracic Surgery , DOI: ( /j.athoracsur ) Copyright © 2018 The Society of Thoracic Surgeons Terms and Conditions
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Supplemental Fig 2 The Annals of Thoracic Surgery , DOI: ( /j.athoracsur ) Copyright © 2018 The Society of Thoracic Surgeons Terms and Conditions
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