1. Interrelationships among chromosome aneuploidy, promoter hypermethylation, and protein expression of the CDKN2A gene in individuals from northern Brazil with gastric adenocarcinoma 
Adriana Costa Guimarães, Eleonidas Moura Lima, André Salim Khayat, Mário Henrique Girão Faria, Silvia Helena Barem Rabenhorst, Márcia Valéria Pitombeira, Paulo Pimentel Assumpção, Marcelo de Oliveira Bahia, Patrícia Danielle Lima de Lima, Marília de Arruda Cardoso Smith, Rommel Rodríguez Burbano 
Cancer Genetics and Cytogenetics 
Volume 179, Issue 1, Pages (November 2007)
DOI: /j.cancergencyto
Copyright © 2007 Elsevier Inc. Terms and Conditions

2. Fig. 1
Cells submitted to fluorescence in situ hybridization (FISH) and immunohistochemistry techniques. (A) Green signals in interphase nuclei indicate chromosome X disomy (A1) and trisomy (A2). (B) Single green signals in interphase nuclei indicate chromosome 9 monosomy. (C, D) Micrographs show nuclear and cytoplasmic staining for p16 protein in diffuse type (C) and intestinal type (D) gastric adenocarcinoma. 200×.
Cancer Genetics and Cytogenetics  , 45-51DOI: ( /j.cancergencyto )
Copyright © 2007 Elsevier Inc. Terms and Conditions

3. Fig. 2
Product analysis by methylation-specific polymerase chain reaction (PCR) technique, using specific primers into CpG islands located on the promoter region of the CDKN2A gene (aliases include p16, p16INK4a). Abbreviations: L, DNA ladder; M, methylated sample; N, normal tissue (control sample); T, tumoral tissue sample; U unmethylated sample.
Cancer Genetics and Cytogenetics  , 45-51DOI: ( /j.cancergencyto )
Copyright © 2007 Elsevier Inc. Terms and Conditions