1. Bellwork: 2/4/16
Highlight key words from your notes yesterday. Write your summary.

2. Project assignments Smallpox 1,2,5 Vibrio cholera Table 1
yellow fever 1,2,5
Polio 1,2,5 spade
Ebola 1,2,5 club
Rabies 3, 4, 6, 7
Measles 3, 4, 6, 7
SARS-CoV 3, 4,6,7 spade
Zika 3, 4,6, 7 club
Vibrio cholera Table 1
Clostridium botulinum Table2
Bordella pertussis Table 3
Yersinia pestis Table 4
Salmonella typhi Table 5
Rickettsia rickettsia Table 6
Mycobacterium tuberculosis
Table 7

3. Essential Question: How does a virus reproduce
Essential Question: How does a virus reproduce? Standard: describe viral reproduction (B4C)

4. When a virus invades…

5. Number the ovals on your paper1 2 6 3 7 4 8 5

6. Lysogenic Cycle

7. Lysogenic Cycle Attach to cell Inject DNA/RNA
Integrate/Join virus DNA into cell’s DNA
Wait while cell grows and divides (latency)
Remove virus DNA/RNA
Become active (write on arrow connecting 5 and 6)

8. Lysogenic Cycle
- Viruses

9. Write this on the right of your paper (by oval 3)
Example HIV
Write this on the right of your paper (by oval 3)
Enveloped RNA virus
Waits for months to years
Over time the destruction of white blood cells allows people to get sick from other diseases

10. HIV (arrows) Infecting a T-lymphocyte

11. Transmission

12. Create an analogy………
The Lysogenic Cycle is like a ___________ because __________.

13. Lytic Cycle

14. Lytic Cycle Attach to cell Inject DNA/RNA
Produce (replicate) virus parts
Assemble new virons
Release viruses to infect other cells (lyse/lysis)

15. - Viruses
Lytic Cycle

16. Which part of the lytic cycle is shown below?

17. Write this on the right of your paper (by oval 6)
Example Influenza A
Enveloped virus with a segmented RNA
Symptoms appear within days
Infects a wide range of animals other than humans
Undergoes extensive mutations
Causes the flu
Influenza A virus is the second acute infection to be discussed.
Myxovirus
Enveloped virus with a segmented RNA genome
Infects a wide range of animals other than humans
Undergoes extensive antigenic variation
Major cause of respiratory infections

18. Spread of influenza virus
Respiratory aerosoles can be generated from the respiratory tract by various means – from speaking to sneezing.
During a sneeze, millions of tiny droplets of water and mucus are expelled at about 200 miles per hour (100 metres per second). The droplets initially are about micrometres diameter, but they dry rapidly to droplet nuclei of 1-4 micrometres, containing virus particles or bacteria. This is a major means of transmission of several diseases of humans.

19. Weekly consultation rates for influenza and influenza-like illness: Weekly
Returns Service of the Royal College of General Practitioners, 1988 to 1999
100
200
300
400
500
600
Epidemic activity
Higher than expected
seasonal activity
Baseline activity
Rate per population
Normal seasonal activity
Virus epidemiology
Infleunza A virus shows regular outbreaks during the winger months.
These are either
Eopidenics: widespread outbreaks within the coutry
Pandemics: Worldwide outbreaks of the virus affecting large numbers of people.
1988
1989
1990
1991
1992
1993
1994
1995
1996
1997
1998
1999
Year
CDR Weekly Report: 5th November 1999

20. Create an analogy………
The Lytic Cycle is like a ___________ because ___________.

22. Sage and Scribe: Cycle Steps
Get into partners—decide who is partner A and who is partner B.
Partner A: Describe the steps for the Lytic cycle.
Partner B: Draw each step.
After a few minutes, we will switch to the Lysogenic Cycle and you will switch roles.

23. Comic Strip
Create a comic strip to describe a viral reproduction cycle.
If you are at a “Red”, you are doing the lysogenic cycle.
If you are at a “Black”, you are doing the lytic cycle.
Your comic should be 6 “slides” and be the cycle in STORY format