1. Introduction to Biotechnology
Biotechnology I

2. Bellwork
Write down at least five terms that come to mind when you think “Biotechnology.”

3. Essential Question What is Biotechnology ?
What does the field of Biotechnology encompass?
What lead to the Biotechnology revolution?
What type of careers are in Biotechnology?

4. Definition
Biotechnology- The study and manipulation of living things for the purpose of making products that benefit society

5. Biotechnology : The Invisible Revolution
Watch the video
Biotechnology in our everyday lives
Write down how biotechnology is being used to benefit society

6. Domains of Biotechnology
Four major domains
Agricultural Biotechnology
Diagnostic Research Biotechnology
Industrial and Environmental Biotechnology
Medical/Pharmaceutical Biotechnology

7. Industrial and Environmental Biotechnology
Fermented foods and beverages
Genetically engineered proteins for industry
Environmental cleanup
Biosensors, bioterrorism, biodefense

8. Ex: Oil Spill Cleanup
Bacteria genetically engineered to efficiently break down oil left by oil spills
Completion of Treatment

9. Medical/Pharmaceutical Biotechnology
Medicines from plants, animals, fungi
Vaccine and gene therapy
Prosthetics-artificial or engineered organs and tissues
Designer drugs and antibodies
Synthetic skin

10. Ex. Creation of New Vaccines
Production of a recombinant vaccine against human papilloma virus (HPV)r
Virus that causes genital warts and cervical cancer
Given to young adults
Boys up to age 21
Girls up to age 26

11. Agricultural Biotechnology
Breeding of livestock and plant crops
Transgenic plants and animals
Production of plant fibers-biofuels, textiles
Pharmaceuticals in genetically engineered plant crops

12. Ex. Improve Food Nutrition
Genetically engineered rice to produce b-carotene, precursor to vitamin A
High b-carotene content gives rice golden color
Vitamin A deficiency often observed in developing countries
Symptoms of Vitamin A deficiency
Night blindness
Growth retardation of children

13. Diagnostic Research Biotechnology
Genetic testing and screening for diseases
DNA identification and DNA fingerprinting, forensics
Nanotechnology

14. Ex. Genetic Testing
Sequencing the human genome opened new opportunities for genetic testing
Genetic Testing involves examining your DNA for changes that could cause disease
Tests done on collected blood or other tissues

15. Ex. Genetic Testing Used for
Identifying genetic diseases in developing fetuses
Screening newborns for genetic diseases
Screening embryos produced by in vitro fertilization before implantation
Testing adults for genetic diseases before symptoms arise

16. Biotechnology Not a New Industry
Evidence of Biotechnology is observed as early as 2000 BCE
Industry revolutionized with the discovery of DNA structure
Allowed the development of molecular tools that have advanced the science
Examples
Creation of recombinant DNA
DNA sequencing
Polymerase chain reaction

17. Biotechnology Timeline
2000 B.C.E.
Biotechnology used to leaven bread
and ferment beer, using yeast (Egypt)
Production of cheese, fermentation of wine begins (Sumeria, China, Egypt).

18. Biotechnology Timeline
1797
First vaccination
Edward Jenner takes pus from a cowpox lesion,
inserts it into an incision on a boy's arm.
Protects him against smallpox

19. Biotechnology Timeline
1928
Sir Alexander Fleming discovers the antibiotic penicillin by chance when he realizes that Penicillium mold kills bacteria.

20. Biotechnology Timeline
1953
James Watson and Francis Crick describe the double helical structure of DNA.

21. Biotechnology Timeline
1966 The genetic code for DNA is cracked.
Marshall Nirenberg Robert Holley Har Gobind Khorana

22. Biotechnology Timeline
1973
Stanley Cohen and Herbert Boyer perfect genetic engineering techniques to cut and paste DNA using restriction enzymes.
1977- first time human genes expressed in bacteria
Stanley Cohen Herbert Boyer and a recombinant bacterium

23. Biotechnology Timeline
2006
A recombinant vaccine against humanpapillomavirus (HPV) receives FDA approval.

24. Summary Lots of opportunities in Biotechnology
This year in Biotech I will learn the tools the industry commonly uses
Using industry level instruments

25. Assignment: Careers in Biotechnology
Each of you will choose a career from the list provided
Create a 11 X 17 “Want Ad” Poster
Poster must include
Description of the Job Duties
Technical Skills required for the job
Education Requirements
Starting salary for the position
On the back of poster, include URLs where you got your information ( You should have at least two URL)
Make your poster colorful as they will be displayed in the classroom.
Meaning it should be mostly pictures
Poster needs to sell fellow students on career
Put only enough words to meet above requirements