1. Hair shaft
Dermal papillae
Epidermis
Subpapillary
vascular plexus
Papillary
layer
Pore
Appendages
of skin
Dermis
Reticular
layer
• Eccrine sweat
gland
• Arrector pili
muscle
Hypodermis
(superficial fascia)
• Sebaceous
(oil) gland
• Hair follicle
Nervous structures
• Hair root
• Sensory nerve fiber
Cutaneous vascular
plexus
• Pacinian corpuscle
• Hair follicle receptor
(root hair plexus)
Adipose tissue

2. Keratinocytes
Stratum corneum
Most superficial layer; 20–30 layers of dead
cells represented only by flat membranous
sacs filled with keratin. Glycolipids in
extracellular space.
Stratum granulosum
Three to five layers of flattened cells, organelles
deteriorating; cytoplasm full of lamellated gran-
ules (release lipids) and keratohyaline granules.
Epidermal
dendritic
cell
Stratum spinosum
Several layers of keratinocytes unified by
desmosomes. Cells contain thick bundles of
intermediate filaments made of pre-keratin.
Tactile
(Merkel)
cell
Stratum basale
Deepest epidermal layer; one row of actively
mitotic stem cells; some newly formed cells
become part of the more superficial layers.
See occasional melanocytes and epidermal
dendritic cells.
Dermis
Sensory
nerve
ending
(a)
Desmosomes
Melanocyte
Dermis
(b)
Melanin granule

3. Stratum corneum
Most superficial layer; 20–30 layers of dead
cells represented only by flat membranous
sacs filled with keratin. Glycolipids in
extracellular space.
Stratum granulosum
Three to five layers of flattened cells,
organelles deteriorating; cytoplasm full of
lamellated granules (release lipids) and
keratohyaline granules.
Stratum spinosum
Several layers of keratinocytes unified by
desmosomes. Cells contain thick bundles of
intermediate filaments made of pre-keratin.
Stratum basale
Deepest epidermal layer; one row of actively
mitotic stem cells; some newly formed cells
become part of the more superficial layers.
See occasional melanocytes and epidermal
dendritic cells.
Dermis

4. Stratum corneum
Most superficial layer; 20–30 layers of dead
cells represented only by flat membranous
sacs filled with keratin. Glycolipids in
extracellular space.
Keratinocytes
Stratum granulosum
Three to five layers of flattened cells,
organelles deteriorating; cytoplasm full of
lamellated granules (release lipids) and
keratohyaline granules.
Stratum spinosum
Several layers of keratinocytes unified by
desmosomes. Cells contain thick bundles of
intermediate filaments made of pre-keratin.
Stratum basale
Deepest epidermal layer; one row of actively
mitotic stem cells; some newly formed cells
become part of the more superficial layers. See
occasional melanocytes and epidermal
dendritic cells.
Dermis
Desmosomes
Sensory
nerve ending
Melanin granule
Epidermal
dendritic cell
Melanocyte
Tactile
(Merkel) cell

5. Dermis
(b) Papillary layer of dermis, SEM (22,700x)
Light micrograph of thick
skin identifying the extent of
the dermis, (50x)
(c) Reticular layer of dermis, SEM (38,500x)

6. Dermis

9. Friction ridges
Openings of
sweat gland ducts
(a)
(b)

11. CYANOSIS

12. JAUNDICE

13. ERYTHEMA

14. PALLOR

15. BRONZING

16. BRUISING

17. . Sweat pore Sebaceous gland Dermal connective tissue Eccrine gland
gland duct
Hair in
hair follicle
Duct
Dermal
connective
tissue
Secretory cells
(a) Photomicrograph of a
sectioned sebaceous
gland (220x)
(b) Photomicrograph of
a sectioned eccrine
gland (220x)

18. . Sweat pore Sebaceous gland Dermal connective tissue Eccrine
gland duct
Eccrine
gland
Hair in
hair follicle
Secretory cells

19. Sweat pore
Eccrine
gland
Sebaceous
gland
Duct
Dermal connective
tissue
Secretory cells

20. Follicle wall
• Connective tissue
root sheath
• Glassy membrane
• External epithelial
• Internal epithelial
Hair shaft
Hair
• Cuticle
• Cortex
• Medulla
Arrector
pili
(a) Diagram of a cross section of
a hair within its follicle
Sebaceous
gland
Hair root
Hair bulb

21. . Follicle wall • Connective tissue root sheath • Glassy membrane
• External epithelial
root sheath
• Internal epithelial
root sheath
Hair
• Cuticle
• Cortex
Hair shaft
• Medulla
Arrector
pili
(b) Photomicrograph of a cross
section of a hair and hair
follicle (250x)
Sebaceous
gland
Hair root
Hair bulb

22. Hair shaft
Arrector
pili
Sebaceous
gland
Hair root
Follicle wall
• Connective tissue root sheath
Hair bulb
• Glassy membrane
• External epithelial root sheath
• Internal epithelial root sheath
Hair root
• Cuticle
• Cortex
• Medulla
Hair matrix
Hair papilla
Melanocyte
Subcutaneous adipose tissue

23. Follicle wall
• Connective
tissue root sheath
Hair shaft
• Glassy membrane
• External epithelial
root sheath
• Internal epithelial
root sheath
Arrector
pili
Hair root
• Cuticle
Sebaceous
gland
• Cortex
• Medulla
Hair root
Hair matrix
Hair bulb
Hair papilla
Subcutaneous
adipose tissue

24. Lateral
nail fold
Lunule
(a)
Free edge
of nail
Body
of nail
Eponychium
(cuticle)
Proximal
nail fold
Nail bed
Root of nail
Nail
matrix
(b)
Hyponychium
Phalanx (bone of fingertip)

26. Totals 4 1 / % 2
Anterior and posterior
head and neck, 9%
Anterior and posterior
upper limbs, 18%
Anterior
trunk,
18% 1 4 / % 4 1 / %
Anterior and posterior
trunk, 36% 2 2 9% 9%
(Perineum, 1%)
Anterior and posterior
lower limbs, 36%
100%

27. BOILS

28. COLD SORES

29. DECUBITIS

30. IMPETIGO

31. PSORIASIS

32. ROSACEA

33. LECTURE EXAM I COVERS CHAPTERS 1-5 80 QUESTIONS-MC, MATCHING
3 BONUS QUESTIONS