1. Mycobacterium tuberculosis Klebsiella pneumoniae, Legionella pneumophila, Mycobacterium leprae

2. Mycobacterium tuberculosis Bacteria my·co·bac·te·ri·um too-bur-kyuh-loh-sis Puss-ball-like appearance Not gram-stainable Acid fast stain

3. Mycobacterium tuberculosis Tuberculosis Opportunistic pathogen Is the major contributer to tuberculosis, mostly effects the lungs but can also affect bones, CNS and many organs. The contractors immune health is the largest factor of how strongly they are affected.

4. Mycobacterium tuberculosis Treatment Active If you have active TB disease, your doctor will give you several antibiotics to treat the infection and to help prevent resistant bacteria from emerging in your body. You may be taking a combination of antibiotics that may include isoniazid, rifampin, pyrazinamide, or ethambutol for 6 to 12 months. Because active TB disease can be fatal if left untreated, regular monitoring and treatment by a doctor are crucial.

5. Mycobacterium tuberculosis Treatment Resistant A form of TB, called multidrug-resistant TB, is caused by strains of the tuberculosis bacteria that, through mutation, have developed the ability to resist two or more antibiotic drugs. Worldwide, almost half a million people develop this form of TB annually, and about 150,000 die from this disease. An even newer form of TB, called extensively drug-resistant TB, resists almost all TB treatments. Fortunately, this form of TB is still relatively rare. Most cases of TB are still highly treatable if the patient follows the full course of antibiotic treatment.

6. Mycobacterium tuberculosis Pathophysiology Bacteria in droplets that bypass the mucociliary system and reach the alveoli are quickly surrounded and engulfed by alveolar macrophages. After being ingested by macrophages, the mycobacteria continue to multiply slowly, 8 with bacterial cell division occurring every 25 to 32 hours 8

7. Mycobacterium tuberculosis

8. Presentation Coughing for 3 weeks or longer Weight loss Poor appetite Sweating at night Fever Chills Feeling tired or weak Pain in the chest Coughing up blood or brown-colored material

9. Klebsiella pneumoniae Gram-negative bacteria kleb-zee-el-uh noo-mohn-yuh Responsible for a form of pneumonia

10. Legionella pneumophila lee-juh-nel-uh pneu-mo-phila Gram-negative Responsible for Legionnaires Disease

11. Mycobacterium leprae My-cobac-terium lep-rae Gram-negative Responsible for Hansen’s disease