1. The Digestive System

2. The Digestive System
Digestive system: the organ system that is made up of the mouth, esophagus, stomach, intestines, liver, pancreas, and gall bladder; the system that takes in, breaks up, and digests food and then excretes the waste
The digestive system takes in food, digests it, absorbs nutrients and water, and excretes waste.
The digestive system is made up of the digestive tract and accessory organs

3. The Digestive Tract
In most animals, the digestive tract is a long tube with two openings, one at either end.
In humans, the digestive tract consists of the mouth, esophagus, stomach, small intestine, large intestine, and anus.
The digestive tract includes epithelial tissue (produces mucus), smooth muscle tissue, nerves, and connective tissue. The smooth muscle tissue can contract and relax without conscious thought.

4. The Mouth
Digestion begins in the mouth where food is broken down both mechanically (teeth and tongue) and chemically (with enzymes found in saliva that break apart the molecules of food). The tongue moves the food to form a bolus
Pharynx receives food and air; flap-like structure ensures food travels down esophagus.????

5. The Esophagus
The esophagus is a tube consisting of smooth muscle tissue that connects your mouth to your stomach.
The contractions of the smooth muscle (known as peristalsis) slowly moves the food along down the esophagus and into the stomach

6. The Stomach
The main function of the stomach is to hold food and to further break it down by churning it (physical digestion) and with digestive enzymes (chemical digestion).

7. Digestion—Stomach Movement of food in & out by sphincters.
J-shaped stomach has 3 muscles layers to contract, relax, & churn partly digested food.
Stomach cells secrete gastric juice (mixture of hydrochloric acid & enzymes) and mucus.
Mucus protects stomach lining from being digested by gastric juices.
Some absorption of water, medicines (aspirin), and alcohol.
Active enzyme pepsin breaks down proteins

9. The Small Intestine
The intestine consists of: the small intestine and the large intestine.
Most digestion occurs in the small intestine which is about 6 m long and is relatively narrow.
Nutrients (from broken down food) diffuse through the wall of the small intestine into the bloodstream.

10. Digestion—Small Intestine
Up to 7 m in length stretched out; only 2.5 cm diameter.
Partial digestion of food, chyme enters SI
Most chemical digestion takes place in first 25-cm of the duodenum.
Liver produces bile—breaks down fats.
Bile secreted continuously, stored in gallbladder.
Liver detoxifies harmful substances (alcohol).

11. Pancreas secretes digestive enzymes: lipase, trypsin, and pancreatic amylase
Pancreas also produces sodium bicarbonate raises pH of chyme from 2.5 to 9.0
Peptidases in SI complete the digestion of protein
Small intestine secretes maltase to complete breakdown of carbohydrates.

12. Products of Digestion Three macromolecules broken down:
Carbohydrates  glucose
Proteins  amino acids
Fats  fatty acids & glycerol
Food also supplies vitamins & minerals.
All nutrients absorbed into the bloodstream

13. Absorption—Small and Large Intestine
Most absorption in small intestine.
Villi increase surface area up to 10 times.
Large intestine (colon) is 1.5 m long and has twice the diameter as small intestine.
Main function is to absorb water, salt & other usable material.
Bacteria produce vitamin K and some vitamin B.

14. Egestion—Large Intestine
Cellulose reaches large intestine undigested.
Cellulose main component of feces, along with living and dead bacteria and water.
Lack of cellulose may mean fewer bowel movements—risk of developing colon cancer.

16. Digestion and Homeostasis
Nervous, endocrine, circulatory, and digestive systems all control digestion.
Large meals cause more forceful stomach contractions and faster emptying.
Fatty meals slow peristalsis, allowing more time for fat to be absorbed.

17. The Large Intestine
The large intestine, or colon, is larger in diameter than the small intestine but is only about 1.5 m long.
The lining of the large intestine absorbs water from the indigestible food and the remaining solid matter is excreted as feces from the anus.

18. Accessory Organs
The accessory organs are the liver, the gall bladder, and the pancreas. They produce enzymes and other fluids (such as bile) that aid digestion.
Scar tissue forms because of injury or long-term disease

19. Gallstones are hard, pebble-like deposits that form inside the gallbladder. Gallstones may be as small as a grain of sand or as large as a golf ball. Caused by cholesterol, diabetes and liver problems.

20. Accessory Organs
The pancreas produces an enzyme called insulin. Insulin regulates the concentration of glucose (a sugar) in the blood.
Diabetes is a disease in which the pancreas produces too much or too little insulin.

21. Diabetes is a lifelong (chronic) disease in which there are high levels of sugar in the blood. Insulin is a hormone produced by the pancreas to control blood sugar. Diabetes can be caused by too little insulin, resistance to insulin, or both.

24. Accessory Organs
The accessory organs are the liver, the gall bladder, and the pancreas. They produce enzymes and other fluids (such as bile) that aid digestion.

25. Move food (IN to OUT)

26. Four stages of food processing:
Digestive system breaks food down into nutrients, which are absorbed and transported by circulatory system.
Four stages of food processing:
Ingestion – taking in of nutrients (food).
Digestion – breakdown of food (physical & chemical)
Absorption – taking up of digested molecules into cells of digestive tract.
Egestion – removal of waste food materials from body.