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Epidemiology and Biology of Dengue Fever Matthew Braswell BIOL 402 Spring 2014.

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Presentation on theme: "Epidemiology and Biology of Dengue Fever Matthew Braswell BIOL 402 Spring 2014."— Presentation transcript:

1 Epidemiology and Biology of Dengue Fever Matthew Braswell BIOL 402 Spring 2014

2 What is Dengue Fever? WHO.int www.virology.wisconsin.edu

3 About the Dengue virus (DENV1- 4)

4 Symptoms of: Dengue Fever (DF)- vs. Dengue Shock Syndrome (DSS) vs. Dengue Hemorrhagic Fever (DHF) Nature.com

5

6 Who is affected by this virus? Dengue: a continuing global threat

7 How are the virus and/or symptoms treated?

8 Transmission Cycle www.eliminatedengue.com

9 Dengue virus spread within the Human Body Infectionecologyandepidemiology.net Nature.com

10 Infection of a human skin dendritic cell Viralzone.expasy.org

11 “Dissecting the Cell Entry Pathway of Dengue Virus by Single- Particle Tracking in Living Cells” PloS Pathogen Journal 2008 Hilde M. van der Schaar, Michael J. Rust, Chen Chen, Heidi van der Ende-Metselaar, Jan Wilschut, Xiaowei Zhuang; Jolanda M. Smit

12 References http://www.plospathogens.org.libproxy.lib.unc.edu/article/info%3Ad oi%2F10.1371%2Fjournal.ppat.1000244#ppat-1000244-g004 http://www.plospathogens.org.libproxy.lib.unc.edu/article/info%3Ad oi%2F10.1371%2Fjournal.ppat.1000244#ppat-1000244-g004 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626838/pdf/890316 0.pdf http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626838/pdf/890316 0.pdf http://www.biomedcentral.com.libproxy.lib.unc.edu/content/pdf/174 2-7622-2-1.pdf http://www.biomedcentral.com.libproxy.lib.unc.edu/content/pdf/174 2-7622-2-1.pdf Dengue: a continuing global threat. Maria G. Guzman*, Scott B. Halstead‡, Harvey Artsob§, Philippe Buchy||, Jeremy Farrar¶, Duane J. Gubler#, Elizabeth Hunsperger**, Axel Kroeger‡‡, Harold S. Margolis**, Eric Martínez*, Michael B. Nathan§§, Jose Luis Pelegrino*, Cameron Simmons¶, Sutee Yoksan¶¶ and Rosanna W. Peeling‡‡,##. Nature.com


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