2003-2004 Review of Antiulcer Drugs 6 March 2016 11:41 AM.

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Presentation transcript:

Review of Antiulcer Drugs 6 March :41 AM

Aluminum hydroxide Antiulcer Antacid

Atropine Anticholinergic Antimuscarinic Treatment for bradycardia, diarrhea, cholinesterase poisoning

Azithromycin Macrolide antibiotic Bacteriostatic protein synthesis inhibitor 50S ribosome Inhibits translocation

Bismuth subsalicylate Antiulcer Antidiarrheal

Calcium carbonate Antiulcer Antacid

Cimetidine Antihistamine Antiulcer H 2 receptor antagonist

Clarithromycin Macrolide antibiotic Bacteriostatic protein synthesis inhibitor Antiulcer 50S ribosome Inhibits translocation

Doxycycline Tetracycline antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome Prevents aminoacyl tRNA attachment

Erythromycin Macrolide antibiotic Bacteriostatic protein synthesis inhibitor 50S ribosome Inhibits translocation

Lansoprazole Antiulcer H + /K + ATPase inhibitor

Magnesium hydroxide Antiulcer Saline (osmotic) cathartic Antacid

Metronidazole Antibiotic Antiparasitic Antiulcer Anaerobes Reduction leads to intermediates that damage DNA

Misoprostol Prostaglandin

Omeprazole/esomeprazole Antiulcer H + /K + ATPase inhibitor

Pantoprazole Antiulcer H + /K + ATPase inhibitor

Rabeprazole Antiulcer H + /K + ATPase inhibitor

Ranitidine Antihistamine Antiulcer H 2 receptor antagonist

Rebamipide Antiulcer

Sodium bicarbonate Antiulcer Antidote Antacid Alkalinization of urine to treat drug toxicity (esp. barbiturates, salicylates, methanol)

Sucralfate Antiulcer