Function of Sertoli cell Availability of nutrients and supports phagocytosis of discarded spermids cytoplasm Regulation for the release of spermatozoa Secreteion of tubular fluid androgen-binding protein (ABP) inhibin which regulates hormone production Form a part of the blood-testis barrier Availability of nutrients and supports

Blood-Testis Barrier * endothelium of capillary * basement membrane * connective tissue of spermatogenic epith * tight j. of Sertoli cell

Interstitial area of Testis * ~ 34% of total volume * L.C.T with enriched blood and lymphatic vessels * Leydig cells : - large, ovoid acidophilic - round nucleus with dispersed chromatin - apparent nucleoli - secrete androgen

Tubule rectus & Rete testis * no spermatogenic cells * replacement with simple cuboidal epi.

Epididymis *serious tubules connecting rete testis and ductus deferen * three parts: -head: ductuli efferentes -body -tail * functions as accumulation, storage and maturation of spermatozoa ductus epididymidis

Ductuli efferentes * 8-12 convoluted ducts connecting with rete testis * a single layer of epithelial cells with two types: - tall columnar & cilliated c. - short non-ciliated c.

Ductus epididymidis single duct pseudostratified epith. of uniform height sterocilia (microvilli） abundant smooth muscles function of absorption and secretion

Ductus deferens Mucosa Muscularis: Adventitia: Epith.：pseudostratified columnar epith. Mucosa Lamina propria: C.T with enriched elastic f. 3 layers of S.M., inner & outer layers: longitudinal, middle layer: circumferential . Muscularis: Adventitia: fibrosa

Prostate * An aggregative of 3 group of glands Mucosal gland Submucosal gland Main prostate gland * Epith. ranges from simple cuboidal-columnar to pseudostratified columnar * embeded within a fibromuscular stroma