2. The Tissue Level of Organization Group of similar cells –common embryonic origin –common function –bound together by intercellular substance Histology –study of tissues

3. The Origin of Tissues Morula Blastula Gastrula

4. 4 Basic Tissues Types Epithelial Connective Muscle Nervous

5. Epithelial Tissue -- General Features Cover surfaces, line cavities and form glands FUNCTION – To create tissue that line, cover, protect, secrete. Attached to underlying connective tissue by a basement membrane. Cells are tightly packed together, to form tight network. Avascular---without blood vessels –nutrients diffuse in from blood vessels in underlying connective tissue –What does this mean for especially thick epithelia like skin? Rapid cell division; responsive to environmental stresses. Named according to the shape and arrangement of cells.

6. Epithelial Tissues and Their Basement Membrane

7. Simple Squamous Epithelium Single layer of flat cells. – lines blood vessels, form capillary walls, form alveoli. –VERY THIN LAYER--. What is the primary function of this tissue?

8. Examples of Simple Squamous Epithelium Section of intestine Surface view of lining of peritoneal (abdominal) cavity

9. Simple Cuboidal Epithelium Single layer of cube-shaped cells viewed from the side. Cuboidal cells usually are found lining/forming gland ducts.

10. Example of Simple Cuboidal Epithelium Sectional view of kidney tubules.

11. Nonciliated Simple Columnar Unicellular glands =goblet cells secrete mucus –lubricate GI, respiratory, reproductive and urinary systems. Microvilli = fingerlike cytoplasmic projections on the cell membrane’s top surface. Microvilli are designed to increase surface area to increase absorption.

12. Example Nonciliated Simple Columnar Epithelium Section from small intestine The term “brush border” is often used to describe this tissue.

13. Ciliated Simple Columnar Epithelium Single layer of rectangular cells with cilia, cilia are locomotive structures that consist of a 9 +2 arrangement of microtubules that are covered with cell membrane. Mucus from goblet cells moved along by cilia. Why would we want the bronchi and bronchioli lined with this type of tissue?

14. Example Ciliated Simple Columnar Epithelium Section of fallopian tube. Why would we want this structure lined with cilliated columnar cells?

15. Stratified Squamous Epithelium Several cell layers thick Surface cells flat Keratinized = surface cells dead and filled with Keratin protein –Examples include the skin (epidermis) and mucous membranes (non-keratinized) What is the primary function of this type of epithelium?

16. Example of Stratified Squamous Section of vagina

17. Stratified Cuboidal Epithelium Multilayered Surface cells cuboidal – rare (only found in sweat gland ducts & male urethra)

18. Stratified Columnar Epithelium Multilayered Surface cells columnar Rare (very large ducts & part of male urethra)

19. Multilayered Surface cells varying in shape from round to flat if stretched Lines hollow organs of the urinary tract that expand from within. Transitional Epithelium

20. Single cell layer All cells attach to basement membrane but not all reach free surface Nuclei at varying depths Pseudostratified Columnar PSEUDO = FALSE Non-Ciliated version found in part of male Urethra and in Vas Deferens Ciliated version found in Trachea