6.5 Gene Therapy Pages 249-251. Gene therapy Defective genes are corrected using a normal copy of the gene.

Slides:

Advertisements

Similar presentations

Option F: Microbes and Biotechnology F.3 Microbes and Biotechnology.

Advertisements

 Gene therapy is a technique used to correct defective genes responsible for disease development.  There are several techniques to do this:  Normal.

GENE THERAPY Presented at Paradoxes Sunday School Class, Sierra Madre Congregational Church, June 27, 2004.

Biotechnological techniques

Gene therapy for eye disease UCL Institute of Ophthalmology Department of Genetics An experimental technique that uses the delivery of genetic material.

Advances in Genetics Key Concepts

KEY CONCEPT Genetics provides a basis for new medical treatments.

LO: Be able to describe what gene therapy is and how it could be used.

Biotechnology The use of living systems and organisms to develop or make useful products or processes.

Gene Therapy Can it save us??. What is it? Replacing a mutated gene with a healthy copy of the gene Inactivating, or “knocking out”, a mutated gene that.

LEQ: WHAT ARE THE BENEFITS OF DNA TECHNOLOGY & THE HUMAN GENOME PROJECT? to

Copyright Pearson Prentice Hall 14–3 Human Molecular Genetics 14-3 Human Molecular Genetics.

Fundamentals of Biotechnology

Stem Cells, Cloning, Genetically Modified Organisms and Gene Therapy…

Gene Therapy and Genetic Counseling. Treating Genetic Diseases Protein-based therapiesProtein-based therapies Disease Therapeutic Agent Cystic Fibrosis.

Genes, which are carried on chromosomes, are the basic physical and functional units of heredity. Genes are specific sequences of bases that encode instructions.

Gene Therapy. What is Gene Therapy? Defective genes make non-functional proteins, creating genetic disorders Gene therapy corrects defective genes by.

DNA TECHNOLOGY Transgenic organism Restriction Enzyme

VIRUSES Tobacco mosaic virus Influenza virus Adenovirus Bacteriophage.

Consider: WWWWe get all of our traits from all the generations before us. NNNNaturally, we each have our own probability of something in.

An Overview of the curriculum module available on

Kortlynn Johnson. What is Gene Therapy? A technique for correcting defective genes responsible for disease development 1.

Gene Therapy AP Biology Unit 2 + What is Gene Therapy? A way to treat or cure diseases by inserting the “correct” DNA into the cell. Most promising for.

Experimental Gene Therapy Use On Humans. What is gene therapy? Gene therapy is a method of curing genetic disorders by introducing functioning genes into.

GENE THERAPY. What is gene therapy? Gene therapy is the introduction of normal genes into cells that contain defective genes.

Chapter 8: Genetic Engineering by Mailee Phet by Mailee Phet My Hoa Nguyen.

Day 5 Objective: Explain and apply laws of heredity and their relationship to the structure and function of DNA Agenda: Human Genome Project video with.

Gene Therapy. Gene Therapy is a technique for correcting defective genes responsible for disease development Gene Therapy is a technique for correcting.

Human Cloning. Introduction Cloning- the process of making an identical organism through nonsexual means Cloning- the process of making an identical organism.

Manipulating the Genome 6.4. Recombinant DNA genetic information from different organisms can be combined, forming recombinant DNA.

Jordan Jones Lauren Johnson. What is it? Gene therapy, also known as genetic modification, is a technique for correcting faulty genes that are responsible.

Gene Therapy By: Chris Smith and Darran Prewitt. What is gene therapy? Why is it used? Gene therapy = Introduction of normal genes into cells that contain.

KEY CONCEPT Genetics provides a basis for new medical _____________.

What is gene therapy? Do now: In your own words,

Genetic Testing & Gene Therapy 5.3. Genetic Testing & Gene Therapy (5.3)  Genetic tests look for signs of a disease or disorder in DNA taken from an.

What is... Gene Therapy?. Genes Specific sequence of bases that encode instructions on how to make genes. Genes are passed on from parent to child. When.

DNA Technology. TO DO HUMAN GENOME PROJECT Started in map the 3 billion nucleotide sequencesThe project’s purpose was to discover all the estimated.

Gene Therapy By: Destiny Osborne & Amanda Owens. Gene therapy is an experimental technique that uses genes to treat or prevent disease. In the future,

Gene Therapy. What is Gene Therapy? Gene Therapy is the insertion of genes into an individual’s cells and tissues to treat a disease. Gene Therapy is.

Gene Therapy Mostafa A. Askar NCRRT By M.Sc. In Molecular Biology

Gene Therapy Biology 11: Section 6.5. Learning Goals Students will describe gene therapy Students will describe the process of gene insertion.

Human Disorders and Gene Therapy

Advances in Genetics Key Concepts

What is ... Gene Therapy?.

Gene Therapy By: Ashley Hale & Cody Stevens.

Human Genome Project, Gene Therapy, and Cloning

Gene Therapy Presentation brought to you by: Therapeutic Genes Inc.

National 5 Biology Genetic Engineering Mr G Davidson.

New genes can be added to an organism’s DNA.

Biology Unit 5 Notes: Genetic Engineering

What is the advantage of knowing what each of your genes codes for?

KEY CONCEPT Genetics provides a basis for new medical treatments.

Gene Therapy Learning Goal: To explore gene therapy. Success Criteria:

Homework: Homework Packet 12 Biotech QUEST on Friday

KEY CONCEPT Genetics provides a basis for new medical treatments.

KEY CONCEPT Genetics provides a basis for new medical treatments.

Advances in Genetics Key Concepts

Gene Therapy Section 6.5.

This tobacco plant has been genetically altered so that it contains a firefly gene, which makes it glow. Define genetic engineering in your own words.

KEY CONCEPT Genetics provides a basis for new medical treatments.

KEY CONCEPT Genetics provides a basis for new medical treatments.

Human Genome Project, Gene Therapy, and Cloning

Gene Therapy (Zinc-finger nuclease, Crisper-CAS 9)

KEY CONCEPT Genetics provides a basis for new medical treatments.

Presentation transcript:

6.5 Gene Therapy Pages

Gene therapy Defective genes are corrected using a normal copy of the gene.

How gene therapy works: Replacing a mutated gene that causes disease with a healthy copy of the gene. Inactivating, or “knocking out,” a mutated gene that is functioning improperly. Introducing a new gene into the body to help fight a disease.

Target cell One of the cells that contain the faulty gene to be corrected.

Vector Any agent, such as a plasmid or a virus, capable of inserting a piece of foreign DNA into a cell.

Limitations Viruses vectors are a good choice for mammals, but plasmid vectors are not. A cold virus is a good choice to target lung cells but not bone cells.

Process Step 1: Remove or alter viral DNA Step 2: Human DNA coding for the normal gene are inserted into virus and incorporated into the viral DNA. Step 3: Large numbers of virus infect human cells.

Tragedies A teenager died in 1999 when he had an unexpected severe immune response to the virus serving as the vector. Leukemia has developed in two children who were treated with gene therapy.

The hurdles: Multiple treatments are required. No control over where gene is inserted. The body may attack the virus. The virus may attack the cell. Many disorders have multiple genes at play. Regulation of genes such as insulin Ability of vector to reach target cells

Successes Restoring vision Restoring hearing Repairing gene causing Duchenne Muscular Dystrophy.

Inherited Blindness Added photoreceptors to dogs to correct vision Children regain sight after pigment layer cells are repaired.

Duchenne Muscular Dystrophy

Deafness Up to 80% of Guinea pigs’ hearing was restored when genes were added to promote the growth of hairs in the cochlea.