Cappiello 2014.  Antigens- red blood cell surface molecules which react with antibodies  Antibodies- carried in blood plasma.

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Presentation transcript:

Cappiello 2014

 Antigens- red blood cell surface molecules which react with antibodies  Antibodies- carried in blood plasma

 Occur for many reasons..  Possible side effects ◦ Aggutination: clumping of red blood cells following a transfusion ◦ Cyanosis ◦ Difficulty breathing

Blood TypeAntigenAntibody AAAnti-B BBAnti-A ABA and BNeither Anti A/B ONeither A or BBoth Anti A/B For example, a person with only antigen A has type A blood. A person with only Antigen B has type B Blood. A person that has AB blood has both antigens A and B and a person with neither antigen A or B has O type blood.

Blood Type of Recipient Preferred Blood Type of Donor Permissible Blood Type of Donor (in emergencies) AAO BBO AB A, B, O OONo alternatives Who is a universal donor? Why? Who is a universal recipient? Why?

 Named after the Rhesus Monkey  Considered “Antigen D” ◦ If the Rh Antigen is present on the blood cell membranes the blood is said to be Rh-positive ◦ If the Rh Antigen is absent the blood is called Rh- negative  Only 15% of the US population is Rh negative  Can be given different Rh factor