Mark Ellisman, PhD Director, National Center for Microscopy and Imaging Research Professor of Neurosciences and Bioengineering University of California at San Diego, School of Medicine Building the BIRN “Biomedical Informatics Research Network (BIRN)”

BRAIN STRUCTURE AND FUNCTION THE CHALLENGE OF MULTIPLE SCALES THE CHALLENGE OF FUNCTIONAL CORRELATIONS

Trans-Pacific Telemicroscopy Tokyo XP (Chicago) STAR TAP TransPAC vBNS (San Diego) SDSC NCMIR (San Diego) UCSD UHVEM (Osaka, Japan) CRL/MPT NCMIR (San Diego) UHVEM (Osaka, Japan) 1 st 2 nd

TELEMICROSCOPY & GRID - BASED COMPUTING REMOTE ACCESS FOR DATA ACQUISITION AND ANALYSIS NETWORK IMAGING INSTRUMENTS COMPUTATIONAL RESOURCES MULTI- SCALE DATA- BASES DATA ACQUISITION DATA ANALYSIS ADVANCED COMPUTER GRAPHICS

National Partnership for Advanced Computational Infrastructure National Center for Research Resources NIH Developing the Grid Cyber Architecture To Support Biomedical Informatics Research Network Developing the Grid Cyber Architecture To Support Biomedical Informatics Research Network Duke UCLA Cal Tech UCSD Harvard NIH/NCRR Centers for BioMedical Imaging and Computational Biololgy UCSD-wide with Medical School Cal-(IT) 2 NPACI/ SDSC “Deep Web” “Surface Web” Integrating Cyber Infrastructure to Link: Advanced Imaging Instruments Data Intensive Computing Multi-Scale Brain Databases Wireless “Pad” Web Interface Form a National Scale Testbed and Federate Multi-scale NeuroImaging Data from Centers with High Field MRI and Advanced 3D MicroscopesBIRN BIRN - Phase I

National Partnership for Advanced Computational Infrastructure National Center for Research Resources NIH “BIRN” is NIH’S BRAND NEW PROJECT to ESTABLISH a B IOMEDICAL I NFORMATICS R ESEARCH N ETWORK