Endocrine System Marie Černá
Regulatory systems Nervous system Endocrine system
Glands Endocrine – hormone-secreting organs, secrete their chemical messengers directly into body fluids (blood) Exocrine – enzyme/mucus-secreting organs, secrete their chemical messengers into ducts that convey the products to the appropriate locations
Endocrine glands 1.Pineal gland 2. Hypothalamus + Pituitary gland 3. Thyroid gland + Parathyroid glands 4.Thymus 5.Adrenal glands 6.Pancreas 7.Ovary (female) 8.Testis (male)
Feedback inhibition
Pineal gland hormonechemical class representative actions regulated by Melatoninamineinvolved in biological rhythms light/dark cycles
Anterior pituitary hormone peptide/protein representative actions regulated by Growth hormoneGH ↑ growth + metabolism hypothalamic h. ProlactinPRL ↑ milk production + secretion hypothalamic h. Thyroid-stimu- lating hormone TSH ↑ thyroid glandhypothalamic h. thyroxine Adrenocortico- tropic hormone ACTH ↑ adrenal cortex → glucocorticoids hypothalamic h. glucocorticoids Follicle-stimu- lating hormone FSH ↑ production of ova and sperm hypothalamic h. Luteinizing hormone LH ↑ ovaries and testes hypothalamic h.
Posterior pituitary hormone peptide representative actions regulated by Antidiuretic hormone ADH↑ retention of water by kidneys water/salt balance Oxytocin↑ contraction of uterus + mammary gland cells nervous system
Thyroid gland
Follicular cells – thyroxine Parafollicular c-cells - calcitonin
Thyroid gland hormone representative actions regulated by T 4 Thyroxine T 3 amine↑ metabolic processesTSH Calcitoninpeptide↓ blood calcium levelcalcium in blood
T 4 Tetraiodothyronine T 3 Triiodothyronine
Parathyroid glands Hormone representative actions regulated by Parathyroid hormone, PTH peptide↑ blood calcium level calcium in blood
Homeostasis: Blood calcium level
Thyroid feedback
Adrenal glands
Medulla: adrenalin (epinephrine) + noradrenalin (norepinephrine) Cortex: z. reticularis – DHA dehydroepiandrosterone z. fasciculata – cortisol (glucocorticoids) z. glomerulosa – aldosterone (mineralocorticoids)
Adrenal medulla Hormone representative actions regulated by adrenalin noradrenalin amine↑ blood glucose level ↑ metabolic activities vessel constriction nervous system
Catecholamines
Synthesis of catecholamines
Adrenal cortex hormone steroid representative actions regulated by Glucocorticoids↑ blood glucose levelACTH Mineralocorticoids↑ reabsorption of Na + + ↑ excretion of K + in kidneys kalium in blood
Steroids hormones
Sex hormones (steroids) Adrenal cortex TestesAndrogens OvariesEstrogens Progesterone
Sex hormones in female
Sex hormones in male
Pancreas
Pancreas Langerhans islets Alpha cells → glucagon Beta cells → insulin
Pancreas hormone peptide representative actions regulated by Insulin↓ blood glucose levelglucose in blood Glucagon↑ blood glucose levelglucose in blood
Circadian rhythms of blood glucose and insulin
Homeostasis: Blood glucose level ↑ blood glucose level Glucagon Glucocorticoids Catecholamines ↓ blood glucose level Insulin
Thymus
Thymus hormonechemical class representative actions regulated by Thymosinpeptidestimulates T lymphocytes
Literature Biology, eighth edition, Campbell, Reece Unit seven: Animal Form and Function Chapter 45: Hormones and the Endocrine System Pages 975 – 996