Beginning of the chapter Thrombosis and genetics (Thrombo Sensor) 36.

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Presentation transcript:

Beginning of the chapter Thrombosis and genetics (Thrombo Sensor) 36

SENSORS THROMBO SENSOR Thrombosis

SENSORS THROMBO SENSOR Skin surface Blood vessels Blood platelets

SENSORS THROMBO SENSORFV Prothrombin FACTOR V (inactive) PROTHROMBIN (inactive)

SENSORS THROMBO SENSOR FACTOR V PROTHROMBIN

SENSORS THROMBO SENSOR

SENSORS THROMBO SENSOR

SENSORS THROMBO SENSOR Factor V activated Thrombin (active)

SENSORS THROMBO SENSOR

SENSORS THROMBO SENSOR

SENSORS THROMBO SENSOR APC

SENSORS THROMBO SENSOR

SENSORS THROMBO SENSORFV Prothrombin FACTOR V PROTHROMBIN

SENSORS THROMBO SENSOR FACTOR V (mutation) PROTHROMBIN

SENSORS THROMBO SENSOR FACTOR V (mutation)

SENSORS THROMBO SENSOR

SENSORS THROMBO SENSOR APC

SENSORS THROMBO SENSOR

SENSORS THROMBO SENSOR Stroke Pulmonary embolism Thrombosis Heart attack

SENSORS THROMBO SENSORFV Prothrombin Venous thrombosis risk PAI1 Arterial thrombosis risk 5 to 25 times increased risk 8 to 80 times increased risk 1.84 times risk

SENSORS Risk factors for thrombosis 10 h sitting (plane) Smoking Surgery/bed rest Women: Hormonal preparations contraceptive pill Hormone replacement therapy Women : pregnancy ? 1.52-times risk ? 2-times risk 4-times risk

End of the chapter Thrombosis and genetics (Thrombo Sensor) 36

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