EXFOLIATIVE DERMATITIS

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Presentation transcript:

EXFOLIATIVE DERMATITIS Lopez, Camille Cecilia S.

a.k.a. dermatitis exfoliativa, pityriasis rubra (Hebra) & erythroderma (Wilson-Brocq) extensive erythema dull scarlet body surface small laminated scales S/s: pruritus, diffuse erythema, epidermal sloughing malaise, and chills Etiology Psoriasis Atopic dermatitis Chronic actinic dermatitis seborrheic dermatitis Pityriasis Rubra pilaris Allergic Contact dermatitis Internal Malignancy Erythrodermic mycosis fungoides Sezary synndrome Medications Andrew’s Diseases of the Skin 9th ed? Medscape

Pathophysiology Increased skin blood perfusion Temperature dysregulation ( heat loss & hypothermia) Basal metabolic rate rises edema, hypoalbuminemia, loss of muscle mass marked loss of exfoliated scales Andrew’s Diseases of the Skin 9th ed? Medscape

In a study of 91 of 102 patients with exfoliative dermatitis by Sigurdsson et al,1 a mortality rate of 43% was observed. No racial predilection is reported for exfoliative dermatitis. Male-to-female ratio is 2-4:1 Usually occurs in persons older than 40 years,

Treatment mid- strength corticosteroid after soaking Acitretin, cyclosporin, methotrexate Immunosuppressive agents ( Azathioprine & Methotrexate) Andrew’s Diseases of the Skin 9th ed? Medscape