Aim: What is Cancer? Do Now: List Five (5) things you already know about cancer Hand in scrapbooks Have out booklet with case study in it Read Part II of case study for tomorrow. Actively read it by underlining and taking notes in the margin HW page 252 due Friday Test on November 19th: Cell Cycle, Mitosis and Cancer (case study included)

What do you know about cancer?

So what is cancer anyway? Cancer is a term for diseases in which abnormal cells divide without control and can invade other tissues. Cancer cells can spread to other parts of the body through the blood and lymph systems (National Cancer institute) Cancer is not just one disease but many diseases. There are more than 100 different types of cancer.

Aim: What are the risk factors associated with Cancer? Do Now: Review Part I and II of the case study. Be ready to answer questions Read Part III of case study for tomorrow. Actively read it by underlining and taking notes in the margin HW page 252 due Friday Test on November 19th: Cell Cycle, Mitosis and Cancer (case study included)

Control of Cell Division ? Contact Inhibition: Cells normally stop multiplying when they come in contact with other cells. This is mediated by cell cycle genes. Cells with mutated cell cycle genes continue to multiply, even when other cells are in close contact.

“Not An Old Person’s Disease” Part 1 “Soaking up the Sun” List the major points in the reading.

Answer the following in pairs What are some differences between Judy and Mariah that might make Judy more “at risk” for skin cancer than Mariah? 2. What observations did Judy make concerning her mole?

Discussion Question #1 Judy Mariah

Discussion Question #2 A-Asymmetry B-Border irregularity C-Color ABCDE’s of Self Examination A-Asymmetry B-Border irregularity C-Color D-Diameter E-Elevation Characteristics of Mole

“Not An Old Person’s Disease” Part 2 “The Basics of Cancer” List the major points in the reading.

Aim: Aim: What are the risk factors associated with Cancer? Do Now: What are some physical traits that might make someone more at risk for skin cancer? Hand in HW HW: Tuesday pg 257 #1-6, 8-10,24, 32-34 Test on Wednesday: Cell Cycle, Mitosis and Cancer (case study included)

Questions Considering the differences between a benign tumor and a malignant tumor, why might a benign tumor be easier to treat? Judy learned that every single person has these cell cycle genes so cells in our body can divide when necessary. What are some normal circumstances where our bodies might need to make more cells? Every person has these cell cycle proto-oncogenes, but not every person has cancer. Why might this be the case? What questions do you think Judy still has?

Review of Do Now Mechanism by which cells become cancerous

Discussion Questions Now that you know a little more, what are the risk factors that increase a person’s chance of having melanoma? How does sunlight contribute to the development of melanoma? What does it mean to be predisposed to getting cancer? If you inherit a mutated cell cycle gene and participate in risky behaviors such as sunbathing, does that mean that you will automatically get cancer some day?