Identical Twins
Genome * The complete set of genetic material in an organism
What is the epigenome?
Epigenome * DNA modifications that do not change the DNA sequence
* Chemical changes (specifically methylation) that regulate can gene activity
Everyone, not just twins, is affected by epigenetic factors
Turn genes on or off
* Brain Cells * Skin Cells
Same genome, different production of proteins!
Epigenetic Tags
*Diet *Sun exposure *Stress
Yellow: Twins shave epigenetic tags in the same place
Red and Green: show where twins have epigenetic tags in different places
Dietary Influences
Nutrient *Resveratrol Epigenetic Role *Removes acetyl groups from histones, improving health
Food? *Red Wine
NutrientEpigenetic Role *DADS*Increased histone acetylation turning on anti- cancer genes
Food? *Garlic
Borderline Personality Disorder B.D.P.
What is it? * Mental illness with persistent long-term symptoms * Impulsive behavior, outbursts and depression
How does it relate to epigenetics and identical twins?
Increased methylation Changes in depression, hopelessness and impulsivity
0%100% Percent of twins who share the trait
Percent of twins who share the trait decreasing 0% 100%
Case Study
Similarities
Careers
Musical Interests
* Largely Innate * “The parents of 394 pairs of twins reported that both twins took music lessons”
Differences
Eye Site
* Genetic aspect * Certain activities --TV/Video games or reading
Height
*About 80% genetic *Nutrition
*Different populations *Caloric intake
Allergies
Environmental Factors *Order of birth with siblings *Exposure to germs *Breast-feeding
What causes allergies? *Immune system Are allergies genetic? *Somewhat
Works Cited