DNA Replication.  Replication = DNA copies itself exactly (Occurs within the nucleus) (Occurs within the nucleus)  Any mistake in copying = mutation.

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DNA Replication

 Replication = DNA copies itself exactly (Occurs within the nucleus) (Occurs within the nucleus)  Any mistake in copying = mutation  DNA mutation = chromosomal mutation

A. Basic Facts of DNA Replication 1. Complementary base pairing makes replication possible C - G A - T

A. Basic Facts of DNA Replication 2. One side of DNA molecule is a template template for making the other side of the strand for making the other side of the strand

B. Process of DNA Replication 1. Uncoil & unzip DNA molecule  Enzyme (-ase) breaks weak Hydrogen Bond between bases

B. Process of DNA Replication 2. Enzyme brings in complementary N-bases DNA Replicase

B. Process of DNA Replication 3. Insert N-bases DNA Replication Tutorial DNA Replication Tutorial

Replication Moovie C - G A - T

C. Semi-conservative replication 1. Each new DNA molecule contains one old strand & one new strand

DNA vs. RNA DNARNA Sugar = deoxyribose Sugar = ribose Double-stranded molecule Single-stranded molecule Thymine bonds with adenine Uracil instead of thymine

DNA vs. RNA DNARNA Nuclear DNA Mitochondrial DNA Chloroplast DNA mRNA = messenger tRNA = transfer rRNA = ribosomal Nuclear DNA never leaves the nucleus Assembled in nucleus, moves to cytoplasm (leaves the nucleus)

DNA vs. vs.RNA