In the name of God.  The cell Summary Slide Cell membrane.

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Presentation transcript:

In the name of God

 The cell

Summary Slide

Cell membrane

Phospholipids

Water transport

Carrier

Endocytosis

Phagocytosis

Pinocytosis

Exocytosis

Signaling pathway

Mitochondria  Summary Slide

Mitochondrion

Mitochondrion

Energy production

Ribosome

Ribosome

protein synthesis

Reticulum endoplasmic

Protein synthesis for export, incorporation in the cell membrane and lysosome   Translation of signal sequence (SS)   Interaction of SS with signal recognition particle (SRP)   Inhibition of continuation of translation   Attachment of SS-SRP complex with docking protein   Detachment of SRP   Continuation of translation   Incorporation of secretary proteins in RER lumen   Removing of SS from protein by signal peptidase

Rough Endoplasmic Reticulum  Segregation of secretary proteins  Phospholipid synthesis  Post-translational modification  Initiation of glycosylation  Assembly of multichain proteins

Smooth endoplasmic reticulum  Steroid synthesis  Phospholipids synthesis  Vesicle  Transfer proteins  Continuation with RER  Sequestration of Ca  Detoxification  Glycogen synthesis

Golgi apparatus  Summary Slide

Golgi Apparatus

Golgi complex

Secretion granule  Summary Slide

Lysosome

Peroxisome  Oxidase  Catalase  Enzyme that involved in lipid metabolism

Proteasome  Digestion of targeted proteins by ubiquitin

CYTOSKELETON  Microfilament Microfilament  Thin filament (actin)  Thick filament (myosin)  Intermediated filament Intermediated  Microtubule Microtubule Antimitotic agents

Tubulin dimer kinesin

Microfilament

Intermediated filament

Intermediated filament Intermediated filament  Epithelial keratin  Mesenchymal cell vimentin  Muscle desmin  Gilial cell gilial fibrillary protein

Function of intermediated filament

Microtubule

Micritubule

Sliding Theory

A 18 years old women consulted with her physician for amnoure. The physician did a lot of test and one of them was sex chromatin assay. The result showed that there was no sex chromatin in the cells. What do you think about the karyotype of her genome.

Nucleus  Nuclear envelope  Chromatin  Nucleolus  Nucleoplasm

Nuclear envelope Nuclear pore

Nucleolus  Nucleolar organizer  Pars fibrosa  Pars granulosa  Nucleolar association chromatin

Nucleolus

Chromatin  Nucleosome  Selenois  Chromosome  Heterochromatin  Euchromatin

Nucleosome

Type of cell size

MEIOSIS

MITOSIS

Regulation of cell cycle  Growth factor  Repair factor (P53)  Maturing promoting factor  Protoncogens

Role of P53 in apoptosis

Apoptotic cell

Comparison of the necrosis with apoptosis