Neuroblastoma 936-8. Case Records Of the Massachusetts General Hospital Case 27-1995 New England Journal of Medicine 1995;333:579-586.

Slides:

Advertisements

Similar presentations

Radiologic Imaging Defines the local extent of a tumor Can be used to stage malignant disease Aids in the diagnosis Monitoring tumor changes after treatment.

Advertisements

NEUROBLASTOMA TA OGUNLESI (FWACP).

Dmitriy Zinovev CSC 594 Final Presentation. Project Description Retrieve current information related to lung abnormalities from the free-text radiological.

Computed Tomography II – RAD 473

Acinic Cell Carcinoma of the Parotid Gland Metastatic to the Epidermis of the Back Pilcher R. Davidson MJC. Department of Oral and Maxillofacial Surgery,

Presentation of a Patient with an Unusual Composite Pheochromocytoma-Ganglioneuroblastoma Iqra Javeed MD 1, Arthur S Tischler MD 2, Michael E Tarnoff MD.

Benign Giant-Cell Tumor of Bone with Metastasis to Mediastinal Lymph Nodes. A Case Report of Resection Facilitated with Use of steroids* by JONATHAN J.

Adrenal tumors by Dr. Gehan Mohamed.

Acquired C797S Mutation upon Treatment with a T790M-Specific Third-Generation EGFR Inhibitor (HM61713) in Non–Small Cell Lung Cancer Haa-Na Song, MD,

Adequacy of Lymph Node Transbronchial Needle Aspirates Using Convex Probe Endobronchial Ultrasound for Multiple Tumor Genotyping Techniques in Non–Small-Cell.

Fig. 2. Mammography images of post radiation sarcoma

Malignant Triton Tumor of the Brachial Plexus Invading the Left Thoracic Inlet: A Rare Differential Diagnosis of Pancoast Tumor Jo Dartnell, BSc, MRCS,

Inflammatory Myofibroblastic Tumor of the Breast Coexisting with Breast Cancer: A Case Report Breast Care 2013;8: DOI: / Fig.

Ground-Glass Centrilobular Nodules on Multidetector CT Scan

Li Ding, Lingling Han, Yin Li, Jing Zhao, Ping He, Weizhen Zhang

Volume 75, Issue 12, Pages (June 2009)

MEDULLARY THYROID CANCER

Recurrent Ventricular Tachycardia in Malignant Metastatic Pheochromocytoma by Ji Won Park, Seung Jung Park, Kyu Yeon Hur, Jung Han Kim, Yoon La Choi, Sun.

Images in Emergency Medicine

Volume 151, Issue 5, Pages e119-e122 (May 2017)

Restoring Balance: Paraneoplastic Cerebellar Degeneration

A 35-Year-Old Patient With Midscapular Pain and Hypertension

Massive: Hemorrhagic Adrenal Pseudocyst

Salma Akram, Darrell S. Pardi, John A. Schaffner, Thomas C. Smyrk

Invasive Inflammatory Myofibroblastic Tumor of the Lung

An Iatrogenic Metastasis

A Predictive Diagnosis: Organizing Pneumonia

Cross-Sectional Imaging of Nontraumatic Peritoneal and Mesenteric Emergencies Michael N. Patlas, MD, FRCPC, Abdullah Alabousi, MD, Mariano Scaglione,

Y-L Chang, MD, C-T Wu, MD, Y-C Lee, MD, PhD

Bilateral Adrenal Adenomas and Persistent Leukocytosis: A Unique Case of Cushing’s Syndrome Nilay Desai, MD, Anoop Kapoor, MD, Binod K. Singh, MD, Jingxuan.

Thymic Hyperplasia after Treatment of ACTH-Dependent Cushing’s Syndrome Can Be Mistaken for a Thymic Epithelial Tumor Jaydira Del Rivero, MD, Chul Kim,

Acquired C797S Mutation upon Treatment with a T790M-Specific Third-Generation EGFR Inhibitor (HM61713) in Non–Small Cell Lung Cancer Haa-Na Song, MD,

A Rarity in a Common Disease: Thyroid Paraganglioma

Sclerosing Pneumocytoma with Lymph Node Metastasis

Surgery Versus Snacking as Treatment of Insulinoma

Slowly Growing Adrenal Mass: A 20-Year Incubation

Ashok K. Malani, MD, MS, Brian Olofsson, MD, David Debono, MD

Uterus-like mass in the left broad ligament misdiagnosed as a malformation of the uterus: A case report of a rare condition and review of the literature

Zeynep Eroglu, MD, Jae Kim, MD, Sharon Wilczynski, MD, PhD, Warren A

Images from the case of a 34-year-old woman who was admitted to the hospital with slight back pain and occasional difficulty swallowing. Images from the.

Dyspnea in a Transplant Recipient With Pulmonary Nodules

Spontaneous regression of a mediastinal thymoma

Miliary Mesothelioma: A New Clinical and Radiological Presentation in Mesothelioma Patients with Prolonged Survival After Trimodality Therapy Lesek Purek,

Muhammad Umair Khawar, MD, Bhaskar Bhardwaj, MD, Himanshu Bhardwaj, MD

Volume 140, Issue 1, Pages (July 2011)

Quiz Page June 2008 American Journal of Kidney Diseases

Adequacy of Lymph Node Transbronchial Needle Aspirates Using Convex Probe Endobronchial Ultrasound for Multiple Tumor Genotyping Techniques in Non–Small-Cell.

Small Cell Transformation and T790M Mutation as Coresistance Mechanisms for First- line Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor.

Makio Hayama, MD, Hiroya Maeda, MD The Annals of Thoracic Surgery

Malignant Triton Tumor of the Brachial Plexus Invading the Left Thoracic Inlet: A Rare Differential Diagnosis of Pancoast Tumor Jo Dartnell, BSc, MRCS,

Volume 141, Issue 1, Pages (January 2012)

Martin H. Chamberlain, FRCS, David P. Taggart, MD, FRCS

A 49-Year-Old Woman With Right Apical Thoracic Mass

Atypical Thymoma (World Health Organization Type B3) with Neuroendocrine Differentiation Combined with Hyperparathyroidism Hyun Sik Park, MD, Sang Wha.

A 45-Year-Old Man With Skin Lesions and Pleural Effusion

Kirsten Brukamp, MD, Simin Goral, MD, Raymond R. Townsend, MD, Frank E

The Heart of the Matter The American Journal of Medicine

Spontaneous Pneumothorax and Lung Carcinoma: Should One Consider Synchronous Malignant Pleural Mesothelioma? Trevor A. Flood, MD, Harman S. Sekhon, MD,

Unusual Cause of Adrenal Insufficiency

Primary intrapulmonary thymoma associated with congenital hyperhomocysteinemia Alessando Stefani, MD, Edouard Boulenger, MD, Sylvie Mehaut, MD, Adrian.

Primary pulmonary artery Rosai-Dorfman disease mimicking sarcoma

Anu Dham, MD, Alexander M. Truskinovsky, MD, Arkadiusz Z

A 40-Year-Old Woman With Multiple Pulmonary Nodules

American Journal of Kidney Diseases

Ground-Glass Centrilobular Nodules on Multidetector CT Scan

Intramuscular hemangioma of the chest wall: An unusual tumor

Mediastinal Mass in a 25-Year-Old Man

Adrenocortical Carcinoma Arising From a Long-standing Adrenal Mass

T-Cell Lymphoma of the Orbit

Mucosa-associated lymphoid tissue lymphoma of the thymus resected using combined thoracoscopic and transcervical approaches Shunsuke Yamada, MD, Kohno.

Presentation transcript:

Neuroblastoma 936-8

Case Records Of the Massachusetts General Hospital Case New England Journal of Medicine 1995;333:

Figure 1. Saggital ultrasound image of the left upper quadrant of the abdomen, showing a heterogenous left adrenal mass.

Figure 2. Contrast-enhanced abdominal CT scan showing a 3.5 cm, heterogenous left adrenal mass.

Figure 3. Sectioned surface of the left adrenal gland showing the tumor surrounded by a thin yellow rim of residual adrenocortical tissue.

Figure 4. Nodular tumor and rim of the adrenal gland (hematoxylin and eosin, x4)

Figure 5. Lymphoid tissue within tumor nodules (hematoxylin and eosin, x48).

Figure 6. Round neuroblasts with a delicate fibrillary background (hematoxylin and eosin, x90).

Figure 7. Ganglion cells mixed with lymphocytes (hematoxylin and eosin, x90).

Paraneoplastic (Neuroblastoma) Opsocolonus Opsoclonus herald sign 2-3% Mean age at onset 16 years Youngest 4 months of age Older than 2 years in only 13% Mediastinal tumor in 49-61% Tumor found within 3 months in 60%

Rarely associated with elevated catecholamines (VMA, HVA metabolites) Anti-neurofilament protein antibodies (M V 210 K) ± in sera Paraneoplastic (Neuroblastoma) Opsocolonus

Survival rate 90% two-year c.f % other neuroblastoma cases Tumor removal may decrease, have no effect or exacerbate opsoclonus Spontaneous resolution may take months or years Paraneoplastic (Neuroblastoma) Opsocolonus