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Benign Giant-Cell Tumor of Bone with Metastasis to Mediastinal Lymph Nodes. A Case Report of Resection Facilitated with Use of steroids* by JONATHAN J.

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Presentation on theme: "Benign Giant-Cell Tumor of Bone with Metastasis to Mediastinal Lymph Nodes. A Case Report of Resection Facilitated with Use of steroids* by JONATHAN J."— Presentation transcript:

1 Benign Giant-Cell Tumor of Bone with Metastasis to Mediastinal Lymph Nodes. A Case Report of Resection Facilitated with Use of steroids* by JONATHAN J. LEWIS, JOHN H. HEALEY, ANDREW G. HUVOS, and MICHAEL BURT J Bone Joint Surg Am Volume 78(1):106-10 January 1, 1996 ©1996 by The Journal of Bone and Joint Surgery, Inc.

2 Computed tomography scan of the chest, made at the time of the initial workup of the mediastinal mass, showing a large mass compressing the superior vena cava in the cephalad part of the anterior mediastinum. JONATHAN J. LEWIS et al. J Bone Joint Surg Am 1996;78:106-10 ©1996 by The Journal of Bone and Joint Surgery, Inc.

3 Computed tomography scan of the chest, made five months after the initial workup of the mediastinal mass, showing considerable regression of the tumor. JONATHAN J. LEWIS et al. J Bone Joint Surg Am 1996;78:106-10 ©1996 by The Journal of Bone and Joint Surgery, Inc.

4 Photomicrograph, made in March 1986, of a specimen from the primary giant-cell tumor of bone, showing numerous osteoclastic multinucleated giant cells and a cellular stroma without cytological atypia. JONATHAN J. LEWIS et al. J Bone Joint Surg Am 1996;78:106-10 ©1996 by The Journal of Bone and Joint Surgery, Inc.

5 Photomicrograph, made in June 1992, of a specimen from the metastatic giant-cell tumor in the mediastinum, demonstrating scattered multinucleated giant cells with a cellular stroma exhibiting no signs of malignant tumor. JONATHAN J. LEWIS et al. J Bone Joint Surg Am 1996;78:106-10 ©1996 by The Journal of Bone and Joint Surgery, Inc.

6 Photomicrograph, made in November 1992, of a specimen from the metastatic giant-cell tumor in a mediastinal lymph node, showing lymphoid tissue of the lymph node on the right (hematoxylin and eosin, x 100). JONATHAN J. LEWIS et al. J Bone Joint Surg Am 1996;78:106-10 ©1996 by The Journal of Bone and Joint Surgery, Inc.


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