Applications of Immunology to Medicine. Some Biochemical Structures Folder Title: ImmunMed Updated: November 21, 2013

General Applications to Medicine Diagnosis Imaging Clinical Laboratory Assays Highly Specific Identification Highly Sensitive Quantitation In Situ Tagging in Whole Cells and Intact Tissues Vaccinations Immune Therapy

Specific Areas of Immunology and Medicine Reacts too Much or Inappropriately. Reacts against Self. Fails to React when it Should. Reacts when we don't want it to. Protects Against Exogenous Pathogens. Viruses Bacteria and Protozoans Fungi Insects and Worms Protects Against Pathogenic Self. Making It Do Its Job Better. Making It Protect Better Suppressing It Augmenting It. Immunity-based Medicinal Agents Allergy/Hypersensitivity Auto-Immune Diseases Immune Deficiency Diseases Transplantation Immunology Infectious Disease Immunity Anti-viral immunity Anti-microbial immunity Anti-fungal immunity Anti-parasitic immunity Tumor Immunology Immune Medicine Vaccines Immuno-suppressive Drugs Immune Adjuvants Monoclonal Antibodies; Cytokines

Immunologically-active Chemical Mediators and Pharmacological Agents Always check-out the organic chemical structures of pharmacologically active agents. They can be more than just unintelligible names.

Serotonin en.wikipedia.org Serotonin or 5-hydroxytryptamine is a monoamine neurotransmitter. Serotonin or 5-hydroxytryptamine is a monoamine neurotransmitter. Biochemically derived from tryptophan, serotonin is primarily found in the gastrointestinal tract, platelets, and in the central nervous system of animals, including humans. It is popularly thought to be a contributor to feelings of well-being and happiness. Chemical formula: C10H12N2O Chemical structure: C1=CC2=C(C=C1O)C(=CN2)CCN IUPAC ID: 5-Hydroxytryptamine L-tryptophan has COOH group here. (No –OH in the indole ring

Histamine (decarboxylated Histidine) Histidine has COOH group here

Epinephrine Epinephrine is a hormone and a neurotransmitter. Epinephrine has many functions in the body, regulating heart rate, blood vessel and air passage diameters, and metabolic shifts; epinephrine release is a crucial component of the fight-or-flight response of the sympathetic ne… Epinephrine is a hormone and a neurotransmitter. Epinephrine has many functions in the body, regulating heart rate, blood vessel and air passage diameters, and metabolic shifts; epinephrine release is a crucial component of the fight-or-flight response of the sympathetic nervous system. In chemical terms, epinephrine is one of a group of monoamines called the catecholamines. It is produced in some neurons of the central nervous system, and in the chromaffin cells of the adrenal medulla from the amino acids phenylalanine and tyrosine. Brand names: EpiPen · Adrenaclick · Medihaler-Epi · TwinjectEpiPenAdrenaclickMedihaler-EpiTwinject May treat: Anaphylaxis · Cardiac arrest · Asthma · Allergy · Ventricular fibrillation · Bradycardia · Ventricular tachycardiaAnaphylaxisCardiac arrestAsthmaAllergyVentricular fibrillationBradycardiaVentricular tachycardia · Septic shock · Hypotension · Heart block · Airway obstruction · Open-angle glaucomaSeptic shockHypotensionHeart blockAirway obstructionOpen-angle glaucoma Drug classes: Catecholamine · Beta-adrenergic agonist · Alpha-Adrenergic AgonistCatecholamineBeta-adrenergic agonistAlpha-Adrenergic Agonist L-tyrosine has COOH group here. Only one hydroxyl group in the para-position on the phenyl ring

Acetylcholine en.wikipedia.org Acetylcholine is an organic molecule that acts as a neurotransmitter in many organisms, including humans. It is an ester of acetic acid and choline, with chemical formula CH 3COO2N+3 and systematic name 2-acetoxy-N,N,N- trimethylethanaminium