Image from: Image by Riedell CELL GROWTH & DIVISION 10-1 & 10-2

Cell Growth and Division Limits to Cell Growth 1.DNA “Overload” 2.Exchanging Materials 3.Ratio of Surface Area to Volume 4.Cell Division

2 Reasons why cells divide 1. _____________________ As cell grows bigger demand on DNA “genetic library” becomes too great Ex: Small town library has 1000 books. As town grows and more people borrow books, there may be a waiting list to read the most popular titles DNA OVERLOAD

2 Reasons why cells divide 2. _____________________ As cell grows bigger demand for transport across membrane is too great Material exchange can’t keep up

Ability to transport of oxygen, food, waste across cell membrane depends on _______________ Need for these depends on ___________ SURFACE AREA CELL VOLUME As cell grows these DON’T increase at the same rate

Go to Section: Cell Size Surface Area (length x width x 6) Volume (length x width x height) Ratio of Surface Area to Volume Ratio of Surface Area to Volume in Cells Section 10-1

When cells get too big, they can’t transport “stuff” fast enough, or in big enough amounts. So cells grow by dividing into many, small cells instead of growing few, bigger cells.

10–2Cell Division A. Chromosomes B. The Cell Cycle C. Events of the Cell Cycle D. Mitosis 1.Prophase 2.Metaphase 3.Anaphase 4.Telophase E. Cytokinesis

SPREAD OUT IN NON-DIVIDING CELLS SCRUNCHED UP IN DIVIDING CELLS CHROMATIN CHROMOSOMES DNA CAN BE:

DNA in PROKARYOTES BACTERIAL DNA is CIRCULAR HAVE ONE CHROMOSOME NO NUCLEUS; ATTACHED TO CELL MEMBRANE

DNA in EUKARYOTES (Plants & Animals) DNA is ROD-SHAPED CHROMOSOMES MANY PAIRS FOUND IN NUCLEUS

All organisms have specific numbers of chromosomes –Humans = _____ Chromosomes –Fruit Flies = 8 Chromosomes –Carrots = 18 Chromosomes Chromosomes (scrunched up DNA) 46

Chromosome structure ___________________ 2 identical arms __________________ constricted area holds chromatids together __________________ PAIR 2 of each chromosome (one from mom; one from dad) CHROMATIDS CENTROMERE HOMOLOGOUS

HOMOLOGOUS CHROMOSOMES SAME SIZE SAME SHAPE CARRY GENES for the SAME TRAITS BUT ______________! (Don’t have to have the SAME CHOICES) NOT IDENTICAL

CELL DIVISION in PROKARYOTES Bacteria reproduce using __________________________________ BINARY FISSION

______________ = series of events that cells go through as they grow and develop CELL CYCLE

INTERPHASE – non-dividing phase G 1 - Grow bigger Cell is “doing its job” DNA is spread out as chromatin S - Synthesis (copy DNA) & chromosomal proteins G 2 - Grow bigger, make organelles & molecules needed for cell division

CELL DIVISION MITOSIS – Nuclear division Prophase Metaphase Anaphase Telophase Cytokinesis – Cytoplasm divides G 0 – cell stops dividing (Ex: nerve cell)

Go to Section: M phase G 2 phase S phase G 1 phase Figure 10–4 The Cell Cycle Section 10-2

INTERPHASE (G 1 - S - G 2 ) In between divisions Cells are in this phase most of the time Can see nucleus DNA spread out as chromatin Can’t see chromosomes DNA gets copied (S) Cell gets ready to divide

PROPHASE 1st dividing phase Spindle fibers form & attach to chromosomes Nuclear membrane & nucleolus disappear DNA scrunches into chromosomes Centrioles appear in centrosome region & move to poles Pearson Education Inc publishing as Pearson Prentice Hall

METAPHASE Chromosomes line up in ___________ middle Microtubules connect the centromere to the two poles of the spindle

ANAPHASE Centromeres split Centrioles pull chromatids_______ apart Anaphase ends when the movement stops

TELOPHASE (reverse prophase steps) See ______ nuclei Nuclear membrane & nucleolus return Chromosomes spread out as chromatin Centrioles disappear Spindle fibers disappear two Images from: Pearson Eduction Ince; Publishing as Pearson Prentice Hall

CYTOKINESIS Cytoplasm splits into 2 cells ANIMAL CELLS pinch cytoplasm in two with a ______________________ CLEAVAGE FURROW

CYTOKINESIS Cytoplasm splits into 2 cells PLANT CELLS can’t pinch because they have a sturdy ____________ Plant cells separate cytoplasm by growing a _______________ down the middle. CELL PLATE CELL WALL

Go to Section: Centrioles Chromatin Interphase Nuclear envelope Cytokinesis Nuclear envelope reforming Telophase Anaphase Individual chromosomes Metaphase Centriole Spindle Centriole Chromosomes (paired chromatids) Prophase Centromere Spindle forming Section 10-2 Figure 10–5 Mitosis and Cytokinesis

Go to Section: Centrioles Chromatin Interphase Nuclear envelope Cytokinesis Nuclear envelope reforming Telophase Anaphase Individual chromosomes Metaphase Centriole Spindle Centriole Chromosomes (paired chromatids) Prophase Centromere Spindle forming Section 10-2 Figure 10–5 Mitosis and Cytokinesis

Go to Section: Centrioles Chromatin Interphase Nuclear envelope Cytokinesis Nuclear envelope reforming Telophase Anaphase Individual chromosomes Metaphase Centriole Spindle Centriole Chromosomes (paired chromatids) Prophase Centromere Spindle forming Section 10-2 Figure 10–5 Mitosis and Cytokinesis

Go to Section: Centrioles Chromatin Interphase Nuclear envelope Cytokinesis Nuclear envelope reforming Telophase Anaphase Individual chromosomes Metaphase Centriole Spindle Centriole Chromosomes (paired chromatids) Prophase Centromere Spindle forming Section 10-2 Figure 10–5 Mitosis and Cytokinesis

Go to Section: Centrioles Chromatin Interphase Nuclear envelope Cytokinesis Nuclear envelope reforming Telophase Anaphase Individual chromosomes Metaphase Centriole Spindle Centriole Chromosomes (paired chromatids) Prophase Centromere Spindle forming Section 10-2 Figure 10–5 Mitosis and Cytokinesis

Go to Section: Centrioles Chromatin Interphase Nuclear envelope Cytokinesis Nuclear envelope reforming Telophase Anaphase Individual chromosomes Metaphase Centriole Spindle Centriole Chromosomes (paired chromatids) Prophase Centromere Spindle forming Section 10-2 Figure 10–5 Mitosis and Cytokinesis

Go to Section: includes is divided into Concept Map Section 10-2 Cell Cycle

Go to Section: includes is divided into Concept Map Section 10-2 Cell Cycle M phase (Mitosis) Interphase G 1 phaseS phaseProphaseG 2 phaseMetaphaseTelophaseAnaphase