Research Opportunities Reserved for Small Business Reserved for Small Business SMALL BUSINESS INNOVATION RESEARCH (SBIR) PROGRAM SMALL BUSINESS TECHNOLOGY.

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Research Opportunities Reserved for Small Business Reserved for Small Business SMALL BUSINESS INNOVATION RESEARCH (SBIR) PROGRAM SMALL BUSINESS TECHNOLOGY TRANSFER (STTR) PROGRAM Updated 01/31/05 (kjs)

SBIR / STTR Program Mission Supporting scientific excellence and technological innovation through the investment of federal research funds in critical American priorities to build a strong national economy… one small business at a time.

Small Business Innovation Research (SBIR) Set-aside program for small business concerns to engage in federal R&D -- with potential for commercialization. Small Business Technology Transfer (STTR) Set-aside program to facilitate cooperative R&D between small business concerns and U.S. research institutions -- with potential for commercialization. Program Descriptions 2.5% 0.3%

WHY SBIR???? Congress designated 4 major goals Small Business Innovation Development Act of 1982 Stimulate technological innovation Use small business to meet federal R&D needs Foster and encourage participation by minorities and disadvantaged persons in technological innovation Increase private-sector commercialization innovations derived from federal R&D

2000 REAUTHORIZATION Program Extension until 9/30/2008 Output and Outcome Data - Public Database: basic award information (Tech-Net Government Database: program evaluation (Phase II awardees -- e.g., new product sale revenues; other investment funding sources) MAJOR PROVISIONS OF P.L ; Signed 12/21/00

WHY STTR???? Small Business Research and Development Enhancement Act of 1992 Stimulate and foster scientific and technological innovation through cooperative research and development carried out between small business concerns and research institutions Foster technology transfer between small business concerns and research institutions

2001 STTR REAUTHORIZATION Reauthorized through FY2009 Set-aside increased from 0.15% to 0.30% in FY 2004 Phase II award levels increased from $500,000 to $750,000 in FY 2004 Participating agencies to implement similar outreach efforts as SBIR

SBIR/STTR: 3-Phase Program PHASE I Ü Feasibility Study Ü $100K and 6-month (SBIR) or 12-month (STTR) Award PHASE II Ü Full Research/R&D Ü $750K and 2-year Award (SBIR/STTR) PHASE III Ü Commercialization Stage Ü Use of non-SBIR/STTR Funds

Organized for- profit U.S. business At least 51% U.S.- owned by individuals and independently operated or it must be a for ‑ profit business concern that is at least 51% owned and controlled by another (one) for-profit business concern that is at least 51% owned and controlled by one or more individuals SBIR PROGRAM ELIGIBILITY CHECKPOINTS ELIGIBILITY CHECKPOINTS

500 employees or fewer including affiliates PI’s primary employment must be with the small business concern at the time of award and for the duration of the project period. SBIR PROGRAM ELIGIBILITY CHECKPOINTS ELIGIBILITY CHECKPOINTS

Applicant is Small Business Concern Subsidiaries are NOT eligible for STTR program Formal Cooperative R&D Effort Ü Minimum 40% by small business Ü Minimum 30% by U.S. research institution U.S. Research Institution College or University; other non-profit research organization; Federal R&D center Intellectual Property Agreement Ü Allocation of Rights in IP and Rights to Carry out Follow-on R&D and Commercialization STTR PROGRAM ELIGIBILITY CHECKPOINTS

SBIR / STTR ELIGIBILITY OWNERSHIP AND CONTROL Contact the SBA Size Specialists Request an eligibility determination got questions?

PERFORMANCE of RESEARCH ACTIVITIES “All research/R&D must be performed in its entirety in the U.S.”  Rare cases to conduct testing of specific patient populations outside U.S. is allowable  Travel to scientific meeting in foreign country allowable  Foreign consultants/collaborators allowable, but must perform consulting in U.S.

FEE/PROFIT Up to 7% of total direct and F&A costs may be requested for fee  Must be REQUESTED/JUSTIFIED in application/proposal  Only SBC eligible; no contracts, consortium or other third party are eligible for fee  Not direct or indirect cost *DISCUSS WITH AGENCIES

DODSBIR/STTR HHSSBIR/STTR NASA SBIR/STTR DOE SBIR/STTR NSF SBIR/STTR DHSSBIR USDASBIR DOCSBIR EDSBIR EPASBIR DOTSBIR SBIR / STTR Participating Agencies TOTAL ~ $2.0 + B FY 2005 New

Standard Phase I Process Agencies describe R&D topics in solicitations. Evaluation Ph I award Solicitation Topics Proposal Submission Small Business Concerns prepare short (usually 25-page)proposals. Unsolicited proposals not accepted. Agencies evaluate based on technical merit, firm’s qualifications, and commercial potential / societal benefit. Agencies make Phase I awards. About 6-9 months

Agency SBIR Differences Number and Timing of Solicitations R&D Topic Areas -- (Broad vs. Focused) Dollar Amount of Award (Phase I and II) Proposal Preparation Instructions Financial details (e.g., Indirect Cost Rates, Gap Funding) Receipt Dates Proposal Review Process Proposal Success Rates Type of Award (Contract or Grant)

Agency SBIR Differences Granting Agencies Ü Investigator initiates approach Ü Less-specified topics Ü Assistance mechanism Ü More flexibility DOD HHS/NIH NASAED EPADOT DOC Contracting Agencies Ü Agency establishes plans, protocols, requirements Ü Highly focused topics Ü Procurement mechanism for DOD and NASA Ü More fiscal requirements HHS/NIH NSF ED USDA DOE

CRITICAL DIFFERENCES SBIR AND STTR PROGRAMS CRITICAL DIFFERENCES Research Partner Research Partner SBIR: Permits research institution partners [Outsource ~ 33% Phase I and 50% Phase II R&D] STTR: Requires research institution partners (e.g., universities) [40% small business concerns (for-profit) and 30% U.S. research institution (non-profit)] AWARD ALWAYS MADE TO SMALL BUSINESS

Principal InvestigatorPrincipal Investigator SBIR: Primary (>50%) employment must be with small business concern STTR: Primary employment not stipulated [PI can be from research institution and/or from small business concern*] *DISCUSS WITH AGENCIES CRITICAL DIFFERENCES SBIR AND STTR PROGRAMS CRITICAL DIFFERENCES

Agency Differences ALWAYS CHECK WITH AGENCIES

Searching Agency Topic Areas Search: Nano AIR FORCE NSF MDA NIH ARMY Utilize Internet Resources ….. List continues

Searching Agency Topic Areas Search: Sensors DARPA DOT NIH NAVY MDA Utilize Internet Resources ….. (cont.)

Searching Agency Solicitations Utilize Internet Resources …. (cont.)

Searching Agency Solicitations Utilize Internet Resources ….. (cont.)

Who Participates in SBIR? Firms are typically small and new to the program. About 1/3 are first-time Phase I awardees. Small hi-tech firms from across the country. *FY01 Phase I DOD Award Winners Firm Size Distribution*

Important Facts to Remember Eligibility is determined at time of award No appendices allowed in Phase I The PI is not required to have a Ph.D. or M.D. The PI is required to have expertise to oversee project scientifically and technically Applications may be submitted to different agencies for similar work Awards may not be accepted from different agencies for duplicative projects

Advice from Awardees Don’t Don’t judge an agency’s interests by name its “name ” agency’s mission & needs Understand agency’s mission & needs agency Program Get to know your agency ProgramManager follow Read solicitation and followinstructions

Advice from Awardees solely Don’t depend solely on SBIR funding alone Don’t go it alone - use support systems outcome Have an outcome get and review Win or lose - get and review evaluations PERSISTENT Be PERSISTENT

Utilize Your State Resources ….. uState=1 STATE CONTACTS

For more information….. l Contact individual agency websites l Cross-agency website: è Conferences / workshops è Topic search engine for all agencies è Partnering Opportunities è State Newsletters

Entrepreneurial Research Institutions Universities / Industry Partnerships and Cultural Differences

UNIVERSITY-BUSINESS PARTNERSHIP OPPORTUNITIES Own small firms (assign someone else PI) Principal Investigator (with official permission from university) Senior Personnel on SBIR/STTR Consultants on SBIR/STTR Subcontracts on SBIR/STTR University facilities provide analytical and other service support

UNIVERSITY AND INDUSTRY: Two diverse cultures Industry Researchers are from MARS are from MARS University Researchers are from Venus are from Venus

UNIVERSITY AND INDUSTRY: Two diverse cultures University culture u Research, discover, educate and train future workforce u Pace is slower - aligned to academic cycle u Mission = basic and applied research u Technology transfer activities are companion to applied research mission u Fertile ground for economic development

UNIVERSITY AND INDUSTRY: Two diverse cultures Industry culture u Mission toward research / R&D / commercialization u Quick-paced u Solve problems - develop new products  profit u Maintain control of science to explore full potential of discovery (initially) u Economic impact: Jobs, societal benefit

CULTURAL DIVERSITY University - Industry Partnerships University - Industry Partnerships Critical dimension of the new “Knowledge-based Economy” u Universities are establishing creative and entrepreneurial environments for the commercialization of university intellectual property u Universities and Industry learning to work together This is now… That was then… is KEY!

u Develop common goals between faculty-initiated business and mission of research institution u Create environment that enables innovation and entrepreneurship u Protect IP assets of university u Establish policies to manage, reduce or eliminate conflict of interest (COI) Entrepreneurial Research Institution Key Ingredients

The Ohio State University Purdue University University of Wisconsin N.C. State University Georgia Tech Virginia Tech Examples of Successful Entrepreneurial Research Institutions Texas A&M University Penn. State University UC San Diego University of Utah Carnegie Mellon University Stanford University Source: Innovation U. “New University Roles in A Knowledge Economy” Southern Technology Council and Southern Growth Policies Board

The Ohio State University Models: Start-ups involving RI employees v Managed Start-Up Model v Faculty-Owned Business Model v Early Stage Development Model v Entrepreneurial Leave Model Examples of Successful Entrepreneurial Research Institutions (cont.)

Purdue Research Park Purdue University: Purdue Research Park  3 business incubators  Companies benefit from shared office concept, flexible leases, attractive rental rates, and more...  Gateways Program  Financial assistance Examples of Successful Entrepreneurial Research Institutions (cont.)

Purdue University  Environment for business to have frequent and mutually beneficial interactions with University  Policies / Procedures to address COI -- not to eliminate, but to minimize and manage Examples of Successful Entrepreneurial Research Institutions (cont.)

Endocyte, Inc. (Purdue Research Park) l Researcher, Philip Low, discovered way to diagnose, potentially cure, ovarian cancer using vitamin folate l Sell technology or start own company to develop and market treatment???? l Resisted VC offers: wanted control of science Now exploring use of folate in arthritis  ADVICE: Hire experienced CEO to handle all but science  BENEFIT: Purdue retains talent SUCCESS STORY

Final Exam The Top 10 List

Top 10 Reasons to Seek SBIR / STTR Funding Opportunities Over $2.0 Billion available 9.NOT A LOAN 9. NOT A LOAN - no repayment Provides recognition, verification and visibility Potential leveraging tool to attract venture capital/other sources of $$$

Top 10 Reasons to Seek SBIR / STTR Funding Opportunities Fosters partnerships (e.g., large corporations, academia) Stimulates local and state economies = stronger national economy Provides seed money to fund high risk projects

Top 10 Reasons to Seek SBIR / STTR Funding Opportunities Intellectual property rights are normally retained by the small business Small business concerns are recognized as a unique national resource of technological innovation

Top 10 Reasons to Seek SBIR / STTR Funding Opportunities To make economic and societal contributions to America