TOXICOLOGY - SLIDE 1 OF 79 © Copyright SafetyInstruction.com CFR 1910 WELCOME INTRODUCTION TO INDUSTRIAL TOXICOLOGY CORPORATE SAFETY TRAINING

TOXICOLOGY - SLIDE 2 OF 79 © Copyright SafetyInstruction.com 2006 COURSE OBJECTIVES  Provide an Introduction to Toxicology  Discuss Toxicology's Role in Today’s Industry.  Discuss General Terms Used in Toxicology.  Discuss the Routes of Entry Into the Human Body.  Discuss the Types of Hazards and Effects.  Discuss the Types of Effects Upon the Human Body.  Discuss Hazard Recognition & Control Skills.

TOXICOLOGY - SLIDE 3 OF 79 © Copyright SafetyInstruction.com 2006 BASIS FOR THIS COURSE  Daily Exposure to Chemical Hazards by Thousands of Workers.  Daily Exposure to Numerous Airborne Contaminants.  Workplace Safety Can Be Greatly Enhanced If Individual Dosages Are Controlled.  OSHA Standards Require: Hazards Be Assessed Training Be Conducted Hazards and Precautions Be Explained Emergency Response Capability Be Established

TOXICOLOGY - SLIDE 4 OF 79 © Copyright SafetyInstruction.com 2006 REGULATORY STANDARD THE GENERAL DUTY CLAUSE FEDERAL - 29 CFR EMPLOYERS MUST: Furnish a place of employment free of recognized hazards that are causing or are likely to cause death or serious physical harm to employees. Employers must comply with occupational safety and health standards promulgated under the Williams- Steiger Occupational Safety and Health Act of OSHA ACT OF 1970

TOXICOLOGY - SLIDE 5 OF 79 © Copyright SafetyInstruction.com 2006 OSHA REGULATIONS 29 CFR REGULATIONS GOVERNING TOXICOLOGY :  Ventilation  Compressed Gases (General Requirements)  Process Safety Management  HAZWOPER  Personal Protective Equipment (General)  Respiratory Protection  Permit-Required Confined Spaces  Medical Services and First Aid  Welding, Cutting and Brazing  Permissible Exposure Limits (Air Contaminants)  Bloodborne Pathogens  Hazard Communication  Laboratory Safety

TOXICOLOGY - SLIDE 6 OF 79 © Copyright SafetyInstruction.com 2006 TRAINING REQUIREMENTS  The Use of Equipment.  What PPE Is Necessary.  When PPE Is Necessary.  The Limitations of the PPE.  Decontamination Procedures.  Engineering Control Operation.  Provide Retraining As Required.  Care and Maintenance of Equipment.  Classification of Hazardous Materials.  Train All Employees Prior to Job Assignment. JOB SAFETY THE EMPLOYER MUST PROVIDE TRAINING :

TOXICOLOGY - SLIDE 7 OF 79 © Copyright SafetyInstruction.com 2006  Close-Call Event.  New Hazard or Equipment.  Change in Job Assignment.  New Hazard Control Methods.  Occupationally Related Injury.  Failure in the Safety Procedures.  Permissible Exposure Exceedance.  Reason to Doubt Employee Proficiency. RETRAINING REQUIREMENTS JOB SAFETY REQUIRED WHEN THERE IS A:

TOXICOLOGY - SLIDE 8 OF 79 © Copyright SafetyInstruction.com 2006 GENERAL TERMS LETS DISCUSS SOME OF THE TERMS THAT WILL BE HELPFUL IN UNDERSTANDING THE BASICS OF TOXICOLOGY. INDUSTRIAL TOXICOLOGY

TOXICOLOGY - SLIDE 9 OF 79 © Copyright SafetyInstruction.com 2006 SPECIFIC GRAVITY Specific Gravity is an abstract or dimensionless number that compares the mass of a liquid to an equal volume of water. Specific Gravity is important to toxicology because, knowing the SG of a liquid can help determine how you could be exposed to it. 1 Gallon of water is 8.33 lbs, (8.33 lbs represents it density). 1 Gallon of Sulfuric Acid is lbs. Specific gravity = = lb/gal (Sulfuric) 8.33 lbs/gal (Water) Density = mass volume

TOXICOLOGY - SLIDE 10 OF 79 © Copyright SafetyInstruction.com 2006 Many chemicals are soluble in water, but when the liquid does not appreciably dissolve in water, the term immiscible is used. SPECIFIC GRAVITY (Continued) WATER IMMISCIBLE IN WATER Float on top if SG less than 1.0 Sink to the bottom if SG greater than 1.0 Easily mixes with water and dissolves SOLUBLE IN WATER

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