BREAST CANCER OVERVIEW Polly Stephens, M.D.
BREAST ANATOMY
breastcancer.org
Ductal Carcinoma In Situ
Calcifications
CALCIFICATIONS
The
Invasive Ductal Carcinoma
Breast cancer
Vascular/Lymphatic Invasion
Bone scan
Liver metastases
MAMMOGRAPHY In America, most breast cancers are diagnosed on mammogram 1 st mammogram age 35 –Or 10 years before your mother was diagnosed with breast cancer Yearly starting age 40 About 10% of cancers are not seen on mammogram. DO YOUR OWN EXAM
St Francis Cancer Institute
BIOPSY Ultrasound-guided Stereotactic MRI guided biopsy
STEREOTACTIC BIOPSY
ULTRASOUND BIOPSY
INVASIVE DUCTAL CARCINOMA Overall survival 75% Stage –0Ductal carcinoma in situ –Itumor <2cm, no lymph nodes –IItumor 2-5cm, <4 lymph nodes –IIItumor >5cm, >4 lymph nodes –IVdistant metastases
INFLAMMATORY BREAST CANCER P’eau d’orange
Treatment Local control –Lumpectomy/mastectomy –Radiation Distal control –Chemotherapy
Sentinel node biopsy
Mammosite
External Beam Radiation
Who needs chemotherapy? If there is a risk of cells in the blood stream looking for a place to settle –Bone, Liver, Lung, Brain There is no blood test for breast cancer cells in the blood stream
Genetics BRCA 1 and 2 –Alterations or mutations in these genes increase ones risk for breast and ovarian cancer –Only about 5% of breast cancer patients are BRCA +