COGNITIVE SCIENCE 17 The Electric Brain Part 2 Jaime A. Pineda, Ph.D.

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Presentation transcript:

COGNITIVE SCIENCE 17 The Electric Brain Part 2 Jaime A. Pineda, Ph.D.

Phases of the Action Potential Firing threshold is the point at which the number of activated Na+ channels > inactivated Na+ channels Absolute refractory period Relative refractory period

Nodes of Ranvier Initial segment

Advantages of myelination Reduces number of ion channels Reduces number of Na+ / K+ pump Increases speed of conduction Reduces energy needs

Saltatory Conduction

Exocytosis

RECEPTORS Ionotropic Metabotropic

Ionotropic Metabotropic Form a channel

Ionotropic Receptor agonist

antagonist

Metabotropic Receptor

(leads to opening of channel)

Upregulation Downregulation Changes to Postsynaptic Receptor Density as a Function of the Amount of Neurotransmitter Released