Gene regulation in prokaryotes March 27, 2006. Inducible transcription: lac operon.

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Presentation transcript:

Gene regulation in prokaryotes March 27, 2006

Inducible transcription: lac operon

Transcription termination by attenuation: trp operon

Transcription termination by attenuation Two possible base- pairing schemes within the mRNA at the beginning of the trp operon

Transcription termination by attenuation Not enough tryptophan amino acids causes ribosome to stall on the mRNA  allows pre- emptor stemloop to form  termination does not occur Moving ribosome  pre-emptor structure does not form – terminator stemloop forms – terminates transcription of the rest of the mRNA

Regulation in phage lambda( )

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