- NeuroLOG workshop Introduction C. Barillot May 18, 2010
Projects Motivations NeuroLog – Computational science & major challenge for this century – population aging – brain disorders growth – brain function understanding – … – Data intensive: – medical image databases, – statistical studies – Heterogeneous, semi- structured, sensitive data sets. – Complex data analysis procedures. – Compute intensive. NeuroLog – Computational science & major challenge for this century – population aging – brain disorders growth – brain function understanding – … – Data intensive: – medical image databases, – statistical studies – Heterogeneous, semi- structured, sensitive data sets. – Complex data analysis procedures. – Compute – To understand from the biomechanical point of view – aneurysm genesis – aneurysm growth – aneurysm rupture – To assess the – risk of aneurysm rupture – risk of aneurysm treatment – To select, when required, the best treatment for each patient, preventing aneurysm growth and rupture – Coiling – Coiling and stent – Flow – To understand from the biomechanical point of view – aneurysm genesis – aneurysm growth – aneurysm rupture – To assess the – risk of aneurysm rupture – risk of aneurysm treatment – To select, when required, the best treatment for each patient, preventing aneurysm growth and rupture – Coiling – Coiling and stent – Flow diverters
Applications NeuroLOG – Multiple sclerosis – Early diagnosis – Evolution prediction – Brain stroke – Lesions volume variations – anatomo-functional relation – Dementia – Commonalities – Data sets: MR modalities, brain anatomy & functions – Processings & procedures: Registration, normalization, skull stripping, tissues classification. NeuroLOG – Multiple sclerosis – Early diagnosis – Evolution prediction – Brain stroke – Lesions volume variations – anatomo-functional relation – Dementia – Commonalities – Data sets: MR modalities, brain anatomy & functions – Processings & procedures: Registration, normalization, skull stripping, tissues – Brain aneurisms – Data: – Genomics – Imaging (MRI, CTA, 3D DSA) – Clinics – – Brain aneurisms – Data: – Genomics – Imaging (MRI, CTA, 3D DSA) – Clinics – Biomechanics
Shared issues
5 NeuroLOG Software architecture
@NeurIST Improve decision making processes Computational design processes to treat ruptured aneurysms knowledge discovery for linking genetics to Systems integration of modeling, simulation and visualization of multimodal integration of data and computing Support Tools Enabling
@neurIST Architecture & Middleware Architectural Overview – Service-Oriented Architecture – Compute & Data Services – Grid & Web Services Grid Middleware – Decoupling of application suites from resources – On-demand computing – Data mediation – Semantic technologies
Projects Numbers NeuroLOG – Project Duration: 45m – Budget: ~1M€ – #teams involved: 9 – #people involved: ~30 NeuroLOG – Project Duration: 45m – Budget: ~1M€ – #teams involved: 9 – #people involved: – Project Duration: 51m – Budget: ~18M€ – #teams involved: 30 – #people involved: – Project Duration: 51m – Budget: ~18M€ – #teams involved: 30 – #people involved: 200+
9 NeuroLOG Partners LRI (Paris XI/CNRS) I3S UNSA/CNRS Visioscopie INRIA Sophia IRISA (INRIA/CNRS) INSERM U836 Business Objects LARIA (U. Picardie/CNRS) IFR 49 (INSERM) software technologies databases and knowledge medical imaging IRISA (INRIA/CNRS) Paris Rennes Grenoble Nice - Sophia Antipolis Amiens 7 academic partners – I3S, IRISA, GIN, MIS, IFR49, INRIA Sophia, LRI 2 companies - SAP, Visioscopie Collaborating hosiptals – Pitié Salpétrière (Paris) – Michalon (Grenoble) – CHU Rennes – Antoine Lacassagne (Nice)
@neurIST Consortium 10
Workshop Program 10:00 Introduction (C. Barillot) 10:20 Summary of the projects and overall set up of the platform – Neurolog: J. Montagnat (20') Gerhard Engelbrecht (20') 11:00 Databases mediation – Neurolog: F. Michel (15') C. Ebeling, S. Benkner (30') – discussion (30') 12:15 Lunch 10:00 Introduction (C. Barillot) 10:20 Summary of the projects and overall set up of the platform – Neurolog: J. Montagnat (20') Gerhard Engelbrecht (20') 11:00 Databases mediation – Neurolog: F. Michel (15') C. Ebeling, S. Benkner (30') – discussion (30') 12:15 Lunch 13:30 Semantic Modeling of data – Neurolog: B. Gibaud, G. Kassel (15') Jesús Bisbal, Martin Boeker (20') – discussion (25') 14:30 Suites and clients – Neurolog: A. Gaignard, J. Montagnat (15') C. Ebeling ? (15') – discussion (30') 15:30 Applications – Neurolog: M. Dojat (15') Christian Ebeling (15') – discussion (30') 16:30 Discussions and wrap up 17:30 Meeting closed 13:30 Semantic Modeling of data – Neurolog: B. Gibaud, G. Kassel (15') Jesús Bisbal, Martin Boeker (20') – discussion (25') 14:30 Suites and clients – Neurolog: A. Gaignard, J. Montagnat (15') C. Ebeling ? (15') – discussion (30') 15:30 Applications – Neurolog: M. Dojat (15') Christian Ebeling (15') – discussion (30') 16:30 Discussions and wrap up 17:30 Meeting closed Objective of the day: Introduce both projects Identify common interests Share experience Compare adopted approaches Objective of the day: Introduce both projects Identify common interests Share experience Compare adopted approaches